1185737-16-9

Basic information

• Product Name: Steviol-19-O-Glucoside
• Synonyms: Steviol-19-O-Glucoside
• CAS NO: 1185737-16-9
• Molecular Weight: 0
• Mol File: 1185737-16-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Steviol-19-O-Glucoside(CAS DataBase Reference)
• NIST Chemistry Reference: Steviol-19-O-Glucoside(1185737-16-9)
• EPA Substance Registry System: Steviol-19-O-Glucoside(1185737-16-9)

Safety Data

• Hazardous Substances Data: 1185737-16-9(Hazardous Substances Data)

Usage

General Description

Steviol-19-O-Glucoside, also known as Rebaudioside D, is a natural sweetener extracted from the leaves of the Stevia rebaudiana plant. It is a glycoside compound that is 250-450 times sweeter than sucrose, making it a popular alternative to sugar in foods and beverages. The compound is stable under a wide range of pH and temperature conditions, making it suitable for use in a variety of products. Additionally, it has been found to have potential health benefits, such as anti-inflammatory and antioxidant properties, and may also help in regulating blood sugar levels. As a result, Steviol-19-O-Glucoside is increasingly being used as a sugar substitute in natural and low-calorie foods and drinks.

Upstream product

• 57817-89-7 stevioside 
• 133-89-1 UDP-glucose 
• 29584-19-8 steviol 
• 51576-10-4 ent-13-acetoxykaur-16-en-19-oic acid 
• 1353022-67-9 C₃₆H₅₀O₁₃ 
• 58543-16-1 rebaudioside A 
• 492-61-5 β-D-glucose 
• 471-80-7 ent-13-hydroxykaur-16-en-19-oic acid 

Relevant articles and documents

Application of 13C NMR spectroscopy to chemistry of natural glycosides: rebaudioside-C, a new sweet diterpene glycoside of Stevia rebaudiana

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Development of Photoaffinity Probe for the Discovery of Steviol Glycosides Biosynthesis Pathway in Stevia rebuadiana and Rapid Substrate Screening

Functional discovery and characterization of the target enzymes responsible for the biosynthesis pathway coded for the genes is ongoing, and the unknown functional diversity of this class of enzymes has been revealed by genome sequencing. Commonly, it is feasible in annotating of biosynthetic genes of prokaryotes due to the existence of gene clusters of secondary metabolites. However, in eukaryotes, the biosynthetic genes are not compactly clustered in the way of prokaryotes. Hence, it remains challenging to identify the biosynthetic pathways of newly discovered natural products in plants. Steviol glycosides are one class of natural sweeteners found in high abundance in the herb Stevia rebaudiana. Here, we applied the chemoproteomic strategy for the proteomic profiling of the biosynthetic enzymes of steviol glycosides in Stevia rebaudiana. We not only identified a steviol-catalyzing UDP-glycosyltransferase (UGT) UGT73E1 involved in steviol glycoside biosynthesis but also built up a probe-based platform for the screening of potential substrates of functional uncharacterized UGT rapidly. This approach would be a complementary tool in mining novel synthetic parts for assembling of synthetic biological systems for the biosynthesis of other complex natural products.

Synthesis of ent-kaurane diterpene monoglycosides

Synthesis of two ent-kaurane diterpene glycosides, steviol 19-O-β-D-glucopyranosiduronic acid (steviol glucuronide, 5), and 13-hydroxy ent-kaur-16-en-19-oic acid-β-D-glucopyranosyl ester (7) has been achieved from a common starting material, steviol, usin