51576-10-4

Basic information

• Product Name: Steviol acetate
• Synonyms: STEVIOLACETATE
• CAS NO: 51576-10-4
• Molecular Formula: C22H32O4
• Molecular Weight: 360.4871
• Mol File: 51576-10-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 469.5°C at 760 mmHg
• Flash Point: 156.6°C
• Appearance: /
• Density: 1.16g/cm³
• Vapor Pressure: 4.11E-10mmHg at 25°C
• Refractive Index: 1.549
• Storage Temp.: -20°C Freezer
• Solubility: Dichloromethane; Ethyl Acetate
• CAS DataBase Reference: Steviol acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Steviol acetate(51576-10-4)
• EPA Substance Registry System: Steviol acetate(51576-10-4)

Safety Data

• Hazardous Substances Data: 51576-10-4(Hazardous Substances Data)

Usage

Description

Steviol acetate is a chemical compound derived from the steviol, which is a primary component of the Stevia plant. It is known for its sweetening properties and is used as an intermediate in the synthesis of various sweeteners.

Uses

Used in the Food and Beverage Industry:
Steviol acetate is used as a sweetening agent for its ability to provide a high level of sweetness without contributing significant calories. It is particularly useful in the development of low-calorie or sugar-free products, catering to health-conscious consumers and those with diabetes.
Used in the Pharmaceutical Industry:
Steviol acetate is used as an intermediate in the synthesis of Steviol Acyl Glucuronide Potassium Salt (S686728), which is a metabolite of Steviol (S686720). This metabolite is the only excretion product found in human urine after the oral intake of Stevioside (90%, S686730), a natural sweetening agent. The pharmaceutical industry utilizes Steviol acetate to develop and enhance sweeteners for various applications, including medications that require sugar-free or low-calorie options.

InChI:InChI=1/C22H32O4/c1-14-12-21-10-6-16-19(3,8-5-9-20(16,4)18(24)25)17(21)7-11-22(14,13-21)26-15(2)23/h16-17H,1,5-13H2,2-4H3,(H,24,25)/t16?,17-,19+,20+,21+,22-/m0/s1

Upstream product

• 29584-19-8 steviol 
• 108-24-7 acetic anhydride 
• 74-95-3 1,1-dibromomethane 

Downstream Products

• 1185737-16-9 13-hydroxy-ent-kaur-16-en-19-oic acid β-D-glucopyranosyl ester 

Relevant articles and documents

SYNTHESIS OF GIBBERELLINS FROM STEVIOL USING THE FUNGUS GIBBERELLA FUJIKUROI

Steviol (ent-13-hydroxykaur-16-en-19-oic acid) was synthesized from steviol acetate norketone (ent-13-acetoxy-16-oxo-17-norkauran-19-oic acid) by the Wittig reaction using (methyl-d3)triphenylphosphonium bromide.A mixture of steviol analogs was produced containing from one to four 2H/molecule. Steviol was fed to strain LM-45-399 the fungus Gibberella fujikuroi which was grown on synthetic medium (ICI, 0percent N) in the presence of the growth retardant CCC. GA1, GA18, GA23 and GA53 were isolated from the fungal medium after 4 days.This strain converted steviol to 13-hydroxy GAs in the highest yields of the four Gibberella strains tested, and in amounts suitable for metabolic studies with higher plants. Key Word Index - Gibberella fujikuroi; fungi; gibberellin biosynthesis; 2H-labelled; GC/MS; GA1; GA18; GA23; GA53; steviol.

Synthesis and biological evaluation of novel exo-methylene cyclopentanone tetracyclic diterpenoids as antitumor agents

The structure of exo-methylene cyclopentanone, which exists in nature tetracyclic diterpenoids products, has been proved to be an innate group for the treatment of cancer and inflammation. In this letter, four different scaffolds of tetracyclic diterpenoi

GIBBERELLINS IN SEEDS OF HELIANTHUS ANNUUS

Fourteen gibberellins (GAs) have been identified in seeds of Helianthus annuus.They comprise the previously known GA1, GA4, GA19, GA20 and GA45 and nine new 15β-hydroxyGAs.Of the new GAs, 15β-hydroxyGA20 and 15β-hydroxyGA1 have been previously synthesized chemically from GA3 and are now assigned the numbers GA67 and GA72.The structures of 15β-hydroxyGA15, 15β-hydroxyGA24 and 15β-hydroxyGA25 were established by their formation from the incubation of ent-15α-hydroxykaur-16-en-19-oic acid with cultures of Gibberella fujikuroi, mutant B1-41a; these new Gas have been respectively assigned the numbers, GA64, GA65 and GA66.The remaining four GAs have been tentatively assigned the structures, 15β-hydroxyGA17, 15β-hydroxyGA19, 15β-hydroxyGA44 and 15β-hydroxyGA53 on the basis of the mass spectra of their MeTMSi derivatives.Abscisic acid, trans-abscisic acid, dihydrophaseic acid, dioxindole-3-acetic acid, ent-7α,16α,17-trihydroxy-16αH-kauranoic acid and ent-7α,16β,17-trihydroxy-and ent-6α,7α,16β,17-tetrahydroxy-16βH-kauranoic acids have also been detected in seeds of Helianthus annuus by capillary GC-MS.From the incubation of ent-15α-hydroxykaur-16-en-19-oic acid with Gibberella fujikuroi, mutant B1-41a, ent-7α,15α-dihydroxykaur-16-en-19-oic acid and 7β,15β-dihydroxykaurenolide have been isolated.Key Word Index - Helianthus annuus; Compositae; sunflower; native gibberellins; new 15β-hydroxygibberellins; microbiological conversion of ent-15α-hydroxykaur-16-en-19-oic acid; Gibberella fujikuroi; mutant B1-41a.