1185742-86-2Relevant articles and documents
A tetranuclear-zinc-cluster-catalyzed practical and versatile deprotection of acetates and benzoates
Iwasaki, Takanori,Agura, Kazushi,Maegawa, Yusuke,Hayashi, Yukiko,Ohshima, Takashi,Mashima, Kazushi
, p. 11567 - 11571 (2010)
A new catalytic deacylation of acetates and benzoates through transesterification with methanol was developed (see scheme). Reactions with various acidand nucleophile-sensitive functional groups proceeded efficiently in the presence of a catalytic amount of the tetranuclear zinc cluster. The present catalysis is applicable to less-reactive tertiary acetates, the deacylation of which is difficult to achieve by transesterification with other catalysts.
