1185881-93-9

Basic information

• Product Name: (2-(3,4,5-trimethoxyphenethyl)phenyl)methanol
• CAS NO: 1185881-93-9
• Molecular Weight: 302.37
• Mol File: 1185881-93-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2-(3,4,5-trimethoxyphenethyl)phenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2-(3,4,5-trimethoxyphenethyl)phenyl)methanol(1185881-93-9)
• EPA Substance Registry System: (2-(3,4,5-trimethoxyphenethyl)phenyl)methanol(1185881-93-9)

Safety Data

• Hazardous Substances Data: 1185881-93-9(Hazardous Substances Data)

Upstream product

• 437611-93-3 2-(2-(3,4,5-trimethoxyphenyl)ethynyl)benzaldehyde 
• 77295-62-6 1,1-Dibromo-2-(3',4',5'-trimethoxyphenyl)ethene 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 53560-33-1 3,4,5-trimethoxyphenylacetylene 

Downstream Products

• 1185881-94-0 2-(3,4,5-trmethoxyphenethyl)benzaldehyde 
• 1185881-56-4 C₂₄H₂₆O₇ 

Relevant articles and documents

Functionalization of Csp3-H bond-Sc(OTf)3-catalyzed domino 1,5-hydride shift/cyclization/Friedel-Crafts acylation reaction of benzylidene Meldrum's acids

Under Sc(OTf)3 catalysis, benzylidene Meldrum's acids bearing a tethered p-methoxyphenethyl group were observed to undergo a [1,5]-hydride shift/cyclization at room temperature, representing a mild Csp3-H bond functionalization. The resulting spiro Meldrum's acid intermediates then underwent intramolecular Friedel-Crafts acylation, completing the one-pot, domino reaction. The reported protocol generates the 6-6-5-6 tetracyclic core of tetrahydrobenzo[b]fluoren-11-ones.