118710-00-2

Basic information

• Product Name: DL-glutamic acid-γ-methyl ester hydrochloride
• Synonyms: DL-glutamic acid-γ-methyl ester hydrochloride
• CAS NO: 118710-00-2
• Molecular Weight: 197.619
• Mol File: 118710-00-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: DL-glutamic acid-γ-methyl ester hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: DL-glutamic acid-γ-methyl ester hydrochloride(118710-00-2)
• EPA Substance Registry System: DL-glutamic acid-γ-methyl ester hydrochloride(118710-00-2)

Safety Data

• Hazardous Substances Data: 118710-00-2(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 617-65-2 Glutamic acid 

Downstream Products

• 118545-57-6 t-butyl 2-tritylamino-4-carbomethoxy-5-hydroxy-5-phenyl-(2RS)-pentanoate 
• 125090-25-7 α-t-butyl γ-methyl N-trityl-(RS)-glutamate 
• 102743-20-4 DL-4-(3,4-dimethyl-benzoyl-amino)-5-(di-n-pentylamino)-5-oxo-pentanoic acid methyl ester 
• 97965-05-4 (+/-)-CR 1398 
• 97964-54-0 4-[(3,4-dimethylbenzoyl)-amino]-5-(dipentylamino)-5-oxopentanoic acid 
• 97964-53-9 (+/-)-CR 1372 
• 97965-17-8 (+/-)-CR 1174 
• 102768-02-5 4-(3,4-Dimethyl-benzoylamino)-4-dimethylcarbamoyl-butyric acid 
• 102743-19-1 DL-N-(3,4-dimethyl-benzoyl)-glutamic acid-γ-methyl ester 
• 23736-76-7 2-Amino-pentanedioic acid 1-tert-butyl ester 5-methyl ester; hydrochloride 

Relevant articles and documents

SYNTHESIS OF NONPROTEINOGENIC AMINO ACIDS PART 2: PREPARATION OF A SYNTHETIC EQUIVALENT OF THE γ-ANION SYNTHON FOR ASYMMETRIC AMINO ACID SYNTHESIS

The synthesis of α-t-butyl γ-methyl N-trityl-(S)-glutamate (12) from (S)-glutamic acid (6) is described.Diester (12), on treatment with lithium isopropylcyclohexylamide followed by the addition of carbonyl compounds, reacts to give the γ-substituted glutamic acid derivatives (13a-i) with retention of optical purity at the α centre.