1187318-53-1

Basic information

• Product Name: methyl 3-bromo-5-fluoro-2-methylbenzoate
• Synonyms: methyl 3-bromo-5-fluoro-2-methylbenzoate;3-BROMO-5-FLUORO-2-METHYL-BENZOIC ACID METHYL ESTER
• CAS NO: 1187318-53-1
• Molecular Formula: C₉H₈BrFO₂
• Molecular Weight: 247.0610232
• EINECS: -0
• Mol File: 1187318-53-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 262.9±40.0 °C(Predicted)
• Appearance: /
• Density: 1.506±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: methyl 3-bromo-5-fluoro-2-methylbenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-bromo-5-fluoro-2-methylbenzoate(1187318-53-1)
• EPA Substance Registry System: methyl 3-bromo-5-fluoro-2-methylbenzoate(1187318-53-1)

Safety Data

• Hazardous Substances Data: 1187318-53-1(Hazardous Substances Data)

Usage

General Description

Methyl 3-bromo-5-fluoro-2-methylbenzoate is a chemical compound with the molecular formula C9H8BrFO2. It is a derivative of benzoic acid and contains methyl, bromine, fluoro, and methyl groups. methyl 3-bromo-5-fluoro-2-methylbenzoate is commonly used as an intermediate in the synthesis of various pharmaceutical and agrochemical products. It is a white solid that is sparingly soluble in water but soluble in organic solvents. Methyl 3-bromo-5-fluoro-2-methylbenzoate is primarily used in research and development processes for the production of new drugs and agricultural chemicals. It is important to handle this compound with proper care and follow safety guidelines due to its potential hazards.

Upstream product

• 175278-29-2 5-fluoro-2-methylbenzoic acid methyl ester 
• 67-56-1 methanol 
• 1187318-52-0 3-bromo-5-fluoro-2-methylbenzoic acid 
• 33184-16-6 5-fluoro-2-methylbenzoic acid 
• 74-88-4 methyl iodide 
• 850462-64-5 5-fluoro-2-methyl-3-nitrobenzoic acid 
• 246877-31-6 3-amino-5-fluoro-2-methylbenzoic acid 

Downstream Products

• 1187318-54-2 methyl 3-bromo-2-(bromomethyl)-5-fluorobenzoate 
• 1255208-37-7 (3-bromo-5-fluoro-2-methyl-phenyl)methanol 
• 1187318-56-4 {[3-bromo-2-(bromomethyl)-5-fluorobenzyl]oxy}(tert-butyl)dimethylsilane 
• 1187318-55-3 [3-bromo-2-(bromomethyl)-5-fluorophenyl]methanol 

Relevant articles and documents

SUBSTITUTED ISOINDOLINONES

Substituted isoindolinones of Formula (I), methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds to treat or ameliorate diseases, disorders, or conditions associated with protein malfunction, such as cancer, are provided.

OXOINDOLINE DERIVATIVES AS PROTEIN FUNCTION MODULATORS

The present invention provides chimeric compounds of formula (II) that modulate protein function, to restore protein homeostasis, including cytokine, aiolos, and/or ikaros activity, TNF-alpha activity, CKl-alpha activity and cell-cell adhesion. The invention provides methods of modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Compositions, including in combination with other cytokine and inflammatory mediators, are provided. Methods of treatment, amelioration, or prevention of protein-mediated diseases, disorders, and conditions, such as cytokine-mediated diseases, disorders, and conditions, including inflammation, fibromyalgia, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, psoriasis, psoriatic arthritis, inflammatory bowel diseases, Crohn's disease, ulcerative colitis, uveitis, inflammatory lung diseases, chronic obstructive pulmonary disease, Alzheimer's disease, organ transplant rejection, and cancer, are provided.