1188274-49-8

Basic information

• Product Name: butyl (Z)-2-methyl-3-(p-toluenesulfonyloxy)prop-2-enoate
• Synonyms: butyl (Z)-2-methyl-3-(p-toluenesulfonyloxy)prop-2-enoate
• CAS NO: 1188274-49-8
• Molecular Weight: 312.387
• Mol File: 1188274-49-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: butyl (Z)-2-methyl-3-(p-toluenesulfonyloxy)prop-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: butyl (Z)-2-methyl-3-(p-toluenesulfonyloxy)prop-2-enoate(1188274-49-8)
• EPA Substance Registry System: butyl (Z)-2-methyl-3-(p-toluenesulfonyloxy)prop-2-enoate(1188274-49-8)

Safety Data

• Hazardous Substances Data: 1188274-49-8(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 115992-39-7 2-methyl-3-oxopropionic acid butyl ester 

Downstream Products

• 92863-46-2 (E)-2-methyl-3-phenylacrylic acid butyl ester 

Relevant articles and documents

Mild, efficient, and robust method for stereocomplementary iron-catalyzed cross-coupling using (E)- and (Z)-enol tosylates

Iron-catalyzed cross-coupling of Grignard reagents (RMgX) with (E)- and (Z)-enol tosylates proceeded smoothly to give a variety of the corresponding (E)- and (Z)-trisubstituted ,-unsaturated methyl esters (total 30 examples; 55-98% yield). The simple, mild, stereoretentive method utilized iron(III) chloride (FeCl3), iron(III) acetylacetonate [Fe(acac)3], and iron(III) tris(dibenzylmethane) [Fe(dbm). The (E)- and (Z)-enol tosylates were readily prepared by the reported stereocomplementary tosylation method from methyl -keto esters or -formyl esters. Methyl -formyl esters were obtained via a practical and robust TiCl4-Et3N-mediated -formylation of methyl esters with methyl formate.