1188366-53-1

Basic information

• Product Name: C₂₆H₂₇NO₁₀S₂
• CAS NO: 1188366-53-1
• Molecular Weight: 577.633
• Mol File: 1188366-53-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₂₇NO₁₀S₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₂₇NO₁₀S₂(1188366-53-1)
• EPA Substance Registry System: C₂₆H₂₇NO₁₀S₂(1188366-53-1)

Safety Data

• Hazardous Substances Data: 1188366-53-1(Hazardous Substances Data)

Upstream product

• 948040-42-4 2,5-anhydro-4,6-di-O-benzoyl-3-O-methanesulfonyl-D-gluconothioamide 
• 868-59-7 L-cysteine ethyl ester hydrochloride 

Downstream Products

• 948040-43-5 ethyl 2-(3,5-di-O-benzoyl-2-O-methanesulfonyl-β-D-arabinofuranosyl)thiazole-4-carboxylate 
• 60084-12-0 2-(4-carboethoxythiazol-2-yl)-5-((benzoyloxy)methyl)furan 

Relevant articles and documents

Synthesis of highly cytotoxic tiazofurin mimics bearing a 2,3-anhydro function in the furanose ring

This paper describes a divergent de novo synthesis of 2-(2,3-anhydro-β-d-ribofuranosyl)thiazole-4-carboxamide (2′,3′-anhydro-tiazofurin) and the corresponding α- and β-homo-C-nucleosides. The synthetic approach was based on a multistep transformation of d-glucose into suitably protected aldonthioamides followed by their subsequent cyclocondensation with ethyl bromopyruvate to form the thiazole ring. Antiproliferative activity of the target molecules is reported against several human tumour cell lines.