1189541-10-3Relevant articles and documents
Fluorescent Sensor for Rapid Detection of Nucleophile and Convenient Comparison of Nucleophilicity
Liu, Kelan,Hu, Yiseng,Xu, Zejun,Yin, Meizhen
, p. 5131 - 5137 (2017)
Although nucleophile (Nu) is associated with many important chemical reactions, there are no fluorescence sensors for Nu detection and even for calculation of its nucleophilicity up to the present. In this study, we developed a fluorescent malononitrile-modified perylenediimide (MAPDI) which can selectively and rapidly react with nucleophiles, such as amines, amino acids, and some inorganic anions, and then change its UV-vis absorption and fluorescence emission. Detection limits of MAPDI for different nucleophiles could be calculated to compare their strength of nucleophilicity. Furthermore, it was found that MAPDI could detect reductive inorganic anions. These results suggested that MAPDI might have a great potential in organocatalytic reactions, metal ion-catalyzed reactions, reactions of amines, and other nucleophilic chemical reactions.
A double function of imine derivative water-soluble [...] synthesis and its application
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Paragraph 0042; 0044, (2016/12/01)
The invention discloses preparation of a double-function water-soluble perylene bisimide derivative and an application of the derivative to a mercury ion probe and a gene carrier. A perylene fluorescent core CHO-PDI carrying four formyl groups is utilized, and a protection reaction is carried out on the formyl groups by sulfydryl to obtain the double-function water-soluble perylene bisimide derivative. On basis of de-protection reaction of mercury ions to the formyl groups of the double-function water-soluble perylene bisimide derivative, the aim of highly-sensitively and highly-selectively rapidly detecting the trace mercury ions in water is realized; the double-function water-soluble perylene bisimide derivative has very good biocompatibility and very low cytotoxicity; an amino with a positive charge is carried at the periphery of a molecule, can enter a live body culture cell and can be combined with DNA (Deoxyribonucleic Acid) or RNA (Ribonucleic Acid) with a negative charge to form a stable compound which is used as a carrier for carrying and protecting an exogenous nucleic acid to enter the live body culture cell. In combination with the two functions, the double-function water-soluble perylene bisimide derivative can be applied to biological cell imaging to detect the mercury ions in the cells.