1189569-77-4Relevant articles and documents
[11C]MK-4232: The first positron emission tomography tracer for the calcitonin gene-related peptide receptor
Bell, Ian M.,Gallicchio, Steven N.,Stump, Craig A.,Bruno, Joseph G.,Fan, Hong,Gantert, Liza T.,Hostetler, Eric D.,Kemmerer, Amanda L.,McWherter, Melody,Moore, Eric L.,Mosser, Scott D.,Purcell, Mona L.,Riffel, Kerry,Salvatore, Christopher A.,Sanabria-Bohorquez, Sandra,Staas, Donnette D.,White, Rebecca B.,Williams, Mangay,Zartman, C. Blair,Cook, Jacquelynn J.,Hargreaves, Richard J.,Kane, Stefanie A.,Graham, Samuel L.,Selnick, Harold G.
supporting information, p. 863 - 868 (2013/10/01)
Rational modification of the potent calcitonin gene-related peptide (CGRP) receptor antagonist MK-3207 led to a series of analogues with enhanced CNS penetrance and a convenient chemical handle for introduction of a radiolabel. A number of 11C-