1190732-26-3

Basic information

• Product Name: N-(4,4-diethoxybutyl)-3-(4-fluoro-phenyl)propionamide
• CAS NO: 1190732-26-3
• Molecular Weight: 311.397
• Mol File: 1190732-26-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4,4-diethoxybutyl)-3-(4-fluoro-phenyl)propionamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4,4-diethoxybutyl)-3-(4-fluoro-phenyl)propionamide(1190732-26-3)
• EPA Substance Registry System: N-(4,4-diethoxybutyl)-3-(4-fluoro-phenyl)propionamide(1190732-26-3)

Safety Data

• Hazardous Substances Data: 1190732-26-3(Hazardous Substances Data)

Upstream product

• 6346-09-4 4-aminobutyrylaldehyde diethylacetal 
• 772-70-3 3-(4-fluorophenyl)propanoyl chloride 

Relevant articles and documents

An investigation into the electrophilic cyclisation of N-acyl-pyrrolidinium ions: A facile synthesis of Pyrrolo-tetrahydroisoquinolones and Pyrrolo-benzazepinones

The triflic acid-mediated cyclisation of N-arylmethyl- and N-arylethyl-acylpyrrolidinium ions gave moderate to good yields of pyrrolo-tetrahydroisoquinolones and pyrrolo-benzazepinones respectively. Electron-donating R substituents enhanced the rate of reaction and gave higher yields than electron-withdrawing substituents. Substituents on the methyl or ethyl chain in general enhanced the reaction, unless sterically encumbered. The equivalent acylpiperidinium ions cyclised much slower and in lower yield.