1192-17-2

Basic information

• Product Name: 2,2-diethyloxirane
• Synonyms: 2-ethyl-1,2-epoxybutane; Oxirane, 2,2-diethyl-
• CAS NO: 1192-17-2
• Molecular Formula: C₆H₁₂O
• Molecular Weight: 100.1589
• Mol File: 1192-17-2.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 106.1°C at 760 mmHg
• Flash Point: 10.4°C
• Density: 0.849g/cm³
• Vapor Pressure: 33.4mmHg at 25°C
• Refractive Index: 1.412
• CAS DataBase Reference: 2,2-diethyloxirane(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-diethyloxirane(1192-17-2)
• EPA Substance Registry System: 2,2-diethyloxirane(1192-17-2)

Safety Data

• Hazardous Substances Data: 1192-17-2(Hazardous Substances Data)

Usage

General Description

2,2-diethyloxirane, also known as ethyl vinyl ether, is a chemical compound with the formula C6H12O. It is a colorless liquid with a faintly sweet odor, and it is highly flammable. 2,2-diethyloxirane is used as a solvent and as an intermediate in the synthesis of other organic compounds. It can also be used as a monomer in the production of polymer materials. However, it is considered to be a hazardous chemical, and exposure to it can cause irritation to the skin, eyes, and respiratory tract. It is important to handle 2,2-diethyloxirane with caution and to use appropriate safety measures when working with this chemical.

Upstream product

• 15642-93-0 3-chloromethyl-pentan-3-ol 
• 760-21-4 2-ethyl-1-butene 

Downstream Products

• 2051-32-3 3-ethyl-3-octanol 
• 597-49-9 3-ethylpentan-3-ol 
• 34577-40-7 3-benzyl-3-pentanol 
• 597-76-2 3-ethyl-3-hexanol 
• 1907-46-6 3-ethyl-5-hexen-3-ol 
• 91328-44-8 3-ethyl-5-methylheptan-3-ol 
• 97-95-0 2-ethyl-1-butanol 
• 1141779-97-6 3-((3-bromophenoxy)methyl)pentan-3-ol 

Relevant articles and documents

Molybdenum containing surface complex for olefin epoxidation

Silica-supported molybdenum surface complexes were prepared by the reaction between (N≡)Mo(OtBu)3 and silica via displacement of the tert-butoxy ligands for siloxyls from the silica surface. The structure of the surface molybdenum complexes was well defined by in-situ FT-IR, elemental analysis, 1H NMR and 13C CP/MAS NMR techniques. The surface complexes could undergo alcoholysis reaction with CD3OD and CH3OH in the same way as free (N≡)Mo(OtBu)3 and they show high catalytic activity and selectivity in olefin epoxidation. Initial rates up to 24.9 mmol epoxide (mmol Mo)-1 min-1 were achieved in the epoxidation of cyclohexene using TBHP as oxidant.

Regioselective Carbonylation of 2,2-Disubstituted Epoxides: An Alternative Route to Ketone-Based Aldol Products

We report the regioselective carbonylation of 2,2-disubstituted epoxides to β,β-disubstituted β-lactones. Mechanistic studies revealed epoxide ring-opening as the turnover limiting step, an insight that facilitated the development of improved reaction conditions using weakly donating, ethereal solvents. A wide range of epoxides can be carbonylated to β-lactones, which are subsequently ring-opened to produce ketone-based aldol adducts, providing an alternative to the Mukaiyama aldol reaction. Enantiopure epoxides were demonstrated to undergo the carbonylation/ring-opening process with retention of stereochemistry to form enantiopure β-hydroxy esters.

AMIDE DERIVATIVES FOR GPR119 AGONIST

The present invention relates to novel amide derivatives, stereoisomers thereof or pharmaceutically acceptable salts thereof; methods for preparing the compound; and pharmaceutical compositions comprising the compound. The novel amide derivatives, according to the present invention, having an effect as GPR119 agonist can be used for treatment of metabolic disorders, including diabetes mellitus (especially type II) and related disorders.