1196474-69-7

Basic information

• Product Name: ethyl 4-(4-formyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)benzoate
• Synonyms: ethyl 4-(4-formyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)benzoate
• CAS NO: 1196474-69-7
• Molecular Formula: C22H25BO6
• Molecular Weight: 396.248
• Mol File: 1196474-69-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 4-(4-formyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-(4-formyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)benzoate(1196474-69-7)
• EPA Substance Registry System: ethyl 4-(4-formyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)benzoate(1196474-69-7)

Safety Data

• Hazardous Substances Data: 1196474-69-7(Hazardous Substances Data)

Upstream product

• 1196474-68-6 ethyl 4-(3-bromo-4-formylphenoxy)benzoate 
• 73183-34-3 bis(pinacol)diborane 
• 120-47-8 Ethyl 4-hydroxybenzoate 
• 59142-68-6 2-bromo-4-fluorobenzaldehyde 

Downstream Products

• 1196473-44-5 ethyl 4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yloxy)benzoate 
• 1196473-95-6 ethyl 4-(1-hydroxy-3-(nitromethyl)-1,3-dihydrobenzo[c][1,2]oxaborol-6-yloxy)benzoate 
• 1196473-94-5 4-(1-Hydroxy-3-(nitromethyl)-1,3-dihydrobenzo[c][1,2]oxaborol-6-yloxy)benzoic acid 

Relevant articles and documents

Synthesis and SAR of novel benzoxaboroles as a new class of β-lactamase inhibitors

A new class of benzoxaborole β-lactamase inhibitors were designed and synthesized. 6-Aryloxy benzoxaborole 22 inhibited AmpC P99 and CMY-2 with K i values in the low nanomolar range. Compound 22 restored antibacterial activity of ceftazidime against Enterobacter cloacae P99 expressing AmpC, a class C β-lactamase enzyme. The SAR around the arylbenzoxaboroles, which included the influence of linker and substitutions was also established.