119724-63-9

Basic information

• Product Name: Boc-Met-Leu-Phe-OBg
• Synonyms: Boc-Met-Leu-Phe-OBg
• CAS NO: 119724-63-9
• Molecular Weight: 732.941
• Mol File: 119724-63-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Boc-Met-Leu-Phe-OBg(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-Met-Leu-Phe-OBg(119724-63-9)
• EPA Substance Registry System: Boc-Met-Leu-Phe-OBg(119724-63-9)

Safety Data

• Hazardous Substances Data: 119724-63-9(Hazardous Substances Data)

Upstream product

• 2488-18-8 N-((tert-butyloxy)carbonyl)-L-methionine p-nitrophenyl ester 
• 119706-37-5 (S)-2-((S)-2-Amino-4-methyl-pentanoylamino)-3-phenyl-propionic acid (benzhydryl-carbamoyl)-methyl ester; compound with trifluoro-acetic acid 

Downstream Products

• 119706-26-2 For-Met-Leu-Phe-OBg 
• 59880-97-6 formyl-methionyl-leucyl-phenylalanine 
• 119724-66-2 (S)-2-[(S)-2-((S)-2-Amino-4-methylsulfanyl-butyrylamino)-4-methyl-pentanoylamino]-3-phenyl-propionic acid (benzhydryl-carbamoyl)-methyl ester; compound with trifluoro-acetic acid 

Relevant articles and documents

N-BENZHYDRYL-GLYCOLAMIDE ESTERS (OBg ESTERS) AS CARBOXYL PROTECTING GROUPS IN PEPTIDE SYNTHESIS

N-benzhydryl-glycolamide esters (OBg esters) of various N-protected amino acids have been synthesized.In order to demonstrate their usefulness in peptide chemistry, the syntheses of For-Met-Leu-Phe-OH (chemiotactic peptide) and Pro-Leu-Gly-NH2 (MIF) have been carried out.OBg esters are compatible with commonly used protecting groups and are cleanly and selectively removed in mild alkaline conditions without any side reaction, except for β-benzyl aspartyl containing sequences.