1198-46-5

Basic information

• Product Name: 2-chloro-6-methoxy-9H-purine
• Synonyms: 2-chloro-6-methoxy-9H-purine
• CAS NO: 1198-46-5
• Molecular Weight: 184.585
• Mol File: 1198-46-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-chloro-6-methoxy-9H-purine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-6-methoxy-9H-purine(1198-46-5)
• EPA Substance Registry System: 2-chloro-6-methoxy-9H-purine(1198-46-5)

Safety Data

• Hazardous Substances Data: 1198-46-5(Hazardous Substances Data)

Usage

General Description

2-chloro-6-methoxy-9H-purine is a chemical compound with the molecular formula C6H5ClN4O and a molar mass of 190.587 g/mol. It is a purine derivative with a chlorine atom at the 2 position and a methoxy group at the 6 position. 2-chloro-6-methoxy-9H-purine is a chlorinated derivative of caffeine, and it has been studied for its potential pharmacological properties. It has been investigated for its potential use as an antiviral agent and as a building block in the synthesis of other bioactive compounds. The compound has also been used in the development of synthetic organic chemistry methods.

Upstream product

• 146196-07-8 2-chloro-9-(2'deoxy-β-D-erythro-pentofuranosyl)-6-methoxy-9H-purine 
• 124-41-4 sodium methylate 
• 5451-40-1 2,6 dichloropurine 
• 67-56-1 methanol 
• 20535-83-5 O<6>-methylguanine 

Downstream Products

• 1318254-92-0 2-chloro-6-methoxy-9-phenyl-9H-purine 
• 1389318-46-0 tert-butyl (2-chloro-6-methoxy-9H-purin-9-yl)(cyclohexyl)methylcarbamate 
• 1275582-97-2 N²-(3,4-dichlorobenzyl)-7-(2-[1-morpholinyl]ethyl)guanine 
• 1338696-08-4 9-benzyl-2-chloro-6-methoxypurine 
• 1370371-06-4 7-benzyl-2-chloro-6-methoxy-7H-purine 

Relevant articles and documents

Determination of 2-chloro-2'-deoxyadenosine (antileukemic agent) and related compounds by electrochemical method

Electrochemical method for determination of 2-chloro-2'-deoxyadenosine and related compounds modified in exocyclic 6-NH2 group is described. Electrochemical detection of investigated compounds, based on the electrooxidation process of the adenine moiety, has been performed in aqueous solutions, in the pH range 2-9, on a glassy carbon electrode.

LRRK2 INHIBITORS AND METHODS OF MAKING AND USING THE SAME

Compounds having the formula (I), (II), (III) are provided. Compounds of the present disclosure are useful for the treatment of neurodegenerative diseases, such as Parkinson's Disease.

Stereocontrolled approach for the syntheses of 3-isopurine nucleosides: 3-(2-deoxy-β-d-ribofuranosyl)xanthine and isoguanine by intramolecular glycosylation

3-Isopurine nucleosides, namely 3-(ribofuranosyl)purine nucleosides, are interesting owing to their potential biological activity and as components of modified oligonucleotides. A regio- and stereocontrolled method was developed for the synthesis of β-2′-