120226-05-3

Basic information

• Product Name: O-benzyloxime of phenolglyoxalic acid methyl ester
• Synonyms: O-benzyloxime of phenolglyoxalic acid methyl ester
• CAS NO: 120226-05-3
• Molecular Weight: 269.3
• Mol File: 120226-05-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: O-benzyloxime of phenolglyoxalic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: O-benzyloxime of phenolglyoxalic acid methyl ester(120226-05-3)
• EPA Substance Registry System: O-benzyloxime of phenolglyoxalic acid methyl ester(120226-05-3)

Safety Data

• Hazardous Substances Data: 120226-05-3(Hazardous Substances Data)

Upstream product

• 2446-83-5 di-isopropyl azodicarboxylate 
• 120225-99-2 N-benzyloxyphenylglycine 
• 37167-62-7 bromo-phenyl-acetic acid methyl ester 
• 622-33-3 N-benzyloxyamine 

Relevant articles and documents

Metal-Free 2,2,6,6-tetramethylpiperidin-1-yloxy radical (TEMPO) catalyzed aerobic oxidation of hydroxylamines and alkoxyamines to oximes and oxime ethers

TEMPO-Mediated oxidation of hydroxylamines (=hydroxyamines) and alkoxyamines to the corresponding oxime derivatives is reported (TEMPO=2,2,6,6-tetramethylpiperidin-1-yloxy radical; Scheme 2). These environmentally benign oxidations proceed in good to excellent yields (Table 1). For alkoxyamines, oxidation to the corresponding oxime ethers can be performed by using dioxygen as a terminal oxidant in the presence of 5-10 mol-% of TEMPO or 4-substituted derivatives thereof as a catalyst (Scheme 3 and Table 2). Importantly, benzyl bromides can directly be transformed to oxime ethers via in situ alkoxyamine formation by a nucleophilic substitution followed by TEMPO-mediated oxidation (Scheme 4 and Table 3). Copyright