1202532-06-6

Basic information

• Product Name: 3-(4-methoxyphenyl)-1-(2-methylphenyl)prop-2-yn-1-one
• Synonyms: 3-(4-methoxyphenyl)-1-(2-methylphenyl)prop-2-yn-1-one
• CAS NO: 1202532-06-6
• Molecular Weight: 250.297
• Mol File: 1202532-06-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-(4-methoxyphenyl)-1-(2-methylphenyl)prop-2-yn-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-methoxyphenyl)-1-(2-methylphenyl)prop-2-yn-1-one(1202532-06-6)
• EPA Substance Registry System: 3-(4-methoxyphenyl)-1-(2-methylphenyl)prop-2-yn-1-one(1202532-06-6)

Safety Data

• Hazardous Substances Data: 1202532-06-6(Hazardous Substances Data)

Upstream product

• 933-88-0 ortho-toluoyl chloride 
• 768-60-5 4-methoxyphenylacetylen 
• 118-90-1 ortho-methylbenzoic acid 

Downstream Products

• 30069-70-6 3-(4-methoxyphenyl)naphthalen-1-ol 
• 5706-14-9 2-[(E)-4-methoxyphenylmethylidene]-1-indanone 
• 1616859-92-7 1-(4-methoxyphenyl)-3-o-tolylprop-2-yn-1-one 

Relevant articles and documents

Cu(II)-Catalyzed 6π-Photocyclization of Non-6πSubstrates

This research successfully achieved a Cu(II)-catalyzed 6π-photocyclization of non-6πsubstrates. The photoenolization converts ortho-alkylphenyl alkynl ketones into a triene-type intermediate which undergoes the subsequent 6π-photocyclization to give napht

Privilege Ynone Synthesis via Palladium-Catalyzed Alkynylation of "Super-Active Esters"

A neat palladium-catalyzed alkynylation reaction was developed with "super-active ester" as the carbonyl electrophile, which provides a clean and efficient synthetic protocol for a broad array of ynone compounds under CO-, Cu-, ligand-, and base-free conditions. The superior activity of triazine ester was rationalized by the strong electron-withdrawing ability and the unique affinity of triazine on palladium. A mechanistic experiment clearly demonstrated that the N-Pd coordination of triazine plays a crucial role for the highly efficient C-O activation. (Chemical Equation presented).

Highly-efficient and recyclable nanosized MCM-41 anchored palladium bipyridyl complex-catalyzed coupling of acyl chlorides and terminal alkynes for the formation of ynones

A highly-efficient and practical method for the formation of ynones from a variety of acyl chlorides and terminal alkynes catalyzed by a nanosized MCM-41 anchored palladium bipyridyl complex is described herein. Aroyl, heteroaroyl, and alkyl acyl chlorides were easily coupled with terminal alkynes, giving good to high isolated yields in the presence of a very low catalyst loading (0.002-0.1 mol % Pd) in Et3N or diisopropylethylamine at 50 °C. Furthermore, the reaction scale was up to 150 mmol for a single batch reaction, providing the potential for practically synthetic application. After centrifugation, the supported catalyst was able to be recycled and reused several times with only a slight decrease in activity.