1203651-07-3

Basic information

• Product Name: (3S,5R)-3-(Boc-aMino)-5-Methylpiperidine
• Synonyms: (3S,5R)-3-(Boc-aMino)-5-Methylpiperidine;tert-butyl N-[(3S,5R)-5-methylpiperidin-3-yl]carbamate;tert-Butyl ((3S,5R)-5-methylpiperidin-3-yl)carbamate;CARBAMIC ACID, N-[(3S,5R)-5-METHYL-3-PIPERIDINYL]-, 1,1-DIMETHYLETHYL ESTER(WX601051)
• CAS NO: 1203651-07-3
• Molecular Formula: C11H22N2O2
• Molecular Weight: 214.30458
• Mol File: 1203651-07-3.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: (3S,5R)-3-(Boc-aMino)-5-Methylpiperidine(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,5R)-3-(Boc-aMino)-5-Methylpiperidine(1203651-07-3)
• EPA Substance Registry System: (3S,5R)-3-(Boc-aMino)-5-Methylpiperidine(1203651-07-3)

Safety Data

• Hazardous Substances Data: 1203651-07-3(Hazardous Substances Data)

Usage

Description

(3S,5R)-3-(Boc-aMino)-5-Methylpiperidine is a chiral organic compound with a unique molecular structure, featuring a piperidine ring with a Boc-protected amino group at the 3-position and a methyl group at the 5-position. (3S,5R)-3-(Boc-aMino)-5-Methylpiperidine is characterized by its stereochemistry, with the 3S and 5R configurations, which are crucial for its reactivity and potential applications.

Uses

Used in Pharmaceutical Industry:
(3S,5R)-3-(Boc-aMino)-5-Methylpiperidine is used as a synthetic intermediate for the preparation of pyridinamine compounds. These compounds act as Pim kinase inhibitors, which are important in the treatment of diseases related to the activity of Pim kinases, such as cancer and other diseases. By inhibiting the activity of Pim kinases, these pyridinamine compounds can help regulate cell growth and division, potentially leading to the suppression of tumor growth and the treatment of cancer.

Upstream product

• 631910-23-1 tert-butyl N-(5-methylpyridin-3-yl)carbamate 
• 3430-19-1 5-methylpyridin-3-amine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1203651-05-1 (2S,4R)-methanesulfonic acid 2-tert-butoxycarbonylamino-5-methanesulfonyloxy-4-methyl-pentyl ester 
• 74936-93-9 (S)-5-oxopyrrolidine-2-carbonyl chloride 
• 4931-66-2 methyl (S)-pyroglutamate 
• 951163-64-7 tert-butyl [(1S,3R)-4-hydroxy-1-(hydroxymethyl)-3-methylbutyl]carbamate 
• 196394-49-7 (2S,4R)-1-(tert-butyl) 2-methyl 4-methyl-5-oxopyrrolidine-1,2-dicarboxylate 
• 108963-96-8 (S)-1-tert-butoxycarbonyl-5-methoxycarbonyl-pyrrolidin-2-one 
• 98-79-3 L-Pyroglutamic acid 
• 1203651-06-2 tert-butyl [(3S,5R)-1-benzyl-5-methylpiperidin-3-yl]carbamate 

Downstream Products

• 1620240-26-7 benzyl [2-{[(4-{(3S,5R)-3-[(tert-butoxycarbonyl)amino]-5-methylpiperidin-1-yl}pyridin-3-yl)amino]carbonyl}-7-(4-methylpiperazin-1-yl)quinolin-3-yl]carbamate 
• 1620240-40-5 benzyl (7-bromo-2-{[(4-{(3S,5R)-3-[(tert-butoxycarbonyl)amino]-5-methylpiperidin-1-yl}pyridin-3-yl)amino]carbonyl}quinolin-3-yl)carbamate 
• 1620240-52-9 benzyl [2-{[(4-{(3S,5R)-3-[(tert-butoxycarbonyl)amino]-5-methylpiperidin-1-yl}pyridin-3-yl)amino]carbonyl}-7-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)quinolin-3-yl]carbamate 
• 1620240-60-9 benzyl [2-{[(4-{(3S,5R)-3-[(tert-butoxycarbonyl)amino]-5-methylpiperidin-1-yl}pyridin-3-yl)amino]carbonyl}-7-(2-oxopiperidin-1-yl)quinolin-3-yl]carbamate 
• 1620240-63-2 benzyl [2-{[(4-{(3S,5R)-3-[(tert-butoxycarbonyl)amino]-5-methylpiperidin-1-yl}pyridin-3-yl)amino]carbonyl}-7-(4-methyl-3-oxopiperazin-1-yl)quinolin-3-yl]carbamate 
• 1620240-67-6 benzyl [2-[({4-[(3S,5R)-3-amino-5-methylpiperidin-1-yl]pyridin-3-yl}amino)carbonyl]-7-(3-oxopiperazin-1-yl)quinolin-3-yl]carbamate 
• 1620240-74-5 benzyl [2-[({4-[(3S,5R)-3-amino-5-methylpiperidin-1-yl]pyridin-3-yl}amino)carbonyl]-7-(3-oxomorpholin-4-yl)quinolin-3-yl]carbamate 
• 1620240-14-3 benzyl (2-{[(4-{(3S,5R)-3-[(tert-butoxycarbonyl)amino]-5-methylpiperidin-1-yl}pyridin-3-yl)amino]carbonyl}-7-morpholin-4-ylquinolin-3-yl)carbamate 

Relevant articles and documents

BICYCLIC HETEROAROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS

The present disclosure describes bicyclic heteroaromatic carboxamide derivatives of formula (I), as well as their compositions and methods of use. The compounds inhibit the activity of the Pim kinases, and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.

BICYCLIC AROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS

The present disclosure describes bicyclic aromatic carboxamide derivatives, as well as their compositions and methods of use. The compounds inhibit the activity of the Pim kinases, and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.

FURO- AND THIENO-PYRIDINE CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS

The present disclosure describes furo- and thieno-pyridine carboxamide compounds, as well as their compositions and methods of use. The compounds inhibit the activity of the Pim kinases, and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.