1203654-47-0

Basic information

• Product Name: N₂-(4-(1H-1,2,4-triazol-1-yl)benzyl)-6-(6-cyclopropoxypyridin-3-yl)-N₄-(2,2,2-trifluoroethyl)pyrido[3,2-d]pyrimidine-2,4-diamine
• CAS NO: 1203654-47-0
• Molecular Weight: 533.516
• Mol File: 1203654-47-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N₂-(4-(1H-1,2,4-triazol-1-yl)benzyl)-6-(6-cyclopropoxypyridin-3-yl)-N₄-(2,2,2-trifluoroethyl)pyrido[3,2-d]pyrimidine-2,4-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: N₂-(4-(1H-1,2,4-triazol-1-yl)benzyl)-6-(6-cyclopropoxypyridin-3-yl)-N₄-(2,2,2-trifluoroethyl)pyrido[3,2-d]pyrimidine-2,4-diamine(1203654-47-0)
• EPA Substance Registry System: N₂-(4-(1H-1,2,4-triazol-1-yl)benzyl)-6-(6-cyclopropoxypyridin-3-yl)-N₄-(2,2,2-trifluoroethyl)pyrido[3,2-d]pyrimidine-2,4-diamine(1203654-47-0)

Safety Data

• Hazardous Substances Data: 1203654-47-0(Hazardous Substances Data)

Upstream product

• 175358-01-7 3-amino-6-chloro-pyridine-2-carboxylic acid amide 
• 766-11-0 5-bromo-2-fluoropyridine 
• 1243318-10-6 5-bromo-2-cyclopropoxypyridine 
• 1318780-09-4 6-cyclopropyloxy-3-pyridinylboronic acid 
• 1318780-08-3 N₂-(4-(1H-1,2,4-triazol-1-yl)benzyl)-6-chloro-N₄-(2,2,2-trifluoroethyl)pyrido[3,2-d]pyrimidine-2,4-diamine 
• 1203655-68-8 2,6-dichloro-N-(2,2,2-trifluoroethyl)pyrido[3,2-d]pyrimidin-4-amine 
• 1036738-12-1 2,4,6-trichloropyrido[3,2-d]pyrimidine 
• 897360-38-2 6-chloropyrido[3,2-d]pyrimidine-2,4(1H,3H)-dione 

Relevant articles and documents

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A novel series of HCV replication inhibitors based on a pyrido[3,2-d]pyrimidine core were optimized for pharmacokinetics (PK) in rats. Several associations between physicochemical properties and PK were identified and exploited to guide the design of comp