120511-92-4 Usage
Description
2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneni is a complex organic compound characterized by its unique molecular structure. It is a derivative of propaneni with a substituted phenyl group, which includes a cyanopropan-2-yl and a 1,2,4-triazol-4-ylmethyl moiety. 2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneni holds potential for various applications due to its distinct chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneni is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential applications in treating different medical conditions.
Used in Chemical Research:
2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneni serves as a valuable research tool in the field of organic chemistry. It can be used to study reaction mechanisms, explore new synthetic routes, and develop novel chemical methodologies.
Used in Material Science:
Due to its structural features, 2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneni may find applications in the development of new materials with specific properties, such as improved stability, reactivity, or selectivity.
Used in Antineoplastic Drug Synthesis:
As seen with Isoanastrozole (Anastrozole EP Impurity G), which is used in the preparation of Anastrozole (A637425), an aromatase inhibitor and antineoplastic agent, 2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneni may also be utilized in the synthesis of antineoplastic drugs, contributing to the development of novel cancer treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 120511-92-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,5,1 and 1 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 120511-92:
(8*1)+(7*2)+(6*0)+(5*5)+(4*1)+(3*1)+(2*9)+(1*2)=74
74 % 10 = 4
So 120511-92-4 is a valid CAS Registry Number.
120511-92-4Relevant articles and documents
A PROCESS FOR PREPARING TRISUBSTITUTED PHENYL DERIVATIVES COMPRISING A (1H-1,2,4-TRIAZOL-1-YL)ALKYL GROUP
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Page/Page column 23-24, (2011/08/03)
The present invention relates in general to the field of organic chemistry, and in particular to the preparation of phenyl derivatives comprising a (1H-1,2,4-triazol-1-yl)alkyl group such as anastrozole (2,2'-(5-((1H-1,2,4-triazol-1-yl)methyl)-1,3-phenylene) bis(2-methyl-propanenitrile).
PURIFICATION PROCESS TO PREPARE HIGHLY PURE ANASTROZOLE
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Page/Page column 9; 10; 11; 11-12; 12; 13, (2009/03/07)
The present invention relates to an industrially advantageous method for the purification of anastrozole of Formula (I), wherein isoanastrozole of Formula (VI), present in crude anastrozole as an impurity, is removed by using gel purification.
Novel processes for preparing substantially pure anastrozole
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Page/Page column 10, (2008/06/13)
The present invention provides novel processes for purifying anastrozole, devoid of using liquid chromatography. The purification processes are via the isolated anastrozole salt forms, either by crystallization or by selective acidic extractions, and optionally in both cases, converting the purified anastrozole salt to anastrozole base. Also provided is an improved process for the synthesis of anastrozole, which is obtained by alkylating the isolated and purified starting material 3,5-bis(2-cyanoprop-2-yl)benzylbromide, the process being devoid of using toxic, hazardous and environmental unfriendly solvents and reagents.
