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1206487-35-5

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1206487-35-5 Usage

General Description

4,6-dibromopyridazin-3-amine is a chemical compound with the molecular formula C4H4Br2N4. It is an organic compound that contains two bromine atoms and an amine group attached to a pyridazine ring. This chemical has potential applications in pharmaceutical research and development, as well as in the synthesis of other organic compounds. It is used as an intermediate in the production of various pharmaceuticals and agrochemicals. Additionally, it may also have some industrial uses in the manufacturing of certain materials. Due to its specific chemical structure, 4,6-dibromopyridazin-3-amine can exhibit unique chemical and physical properties that make it valuable for various scientific and commercial applications.

Check Digit Verification of cas no

The CAS Registry Mumber 1206487-35-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,6,4,8 and 7 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1206487-35:
(9*1)+(8*2)+(7*0)+(6*6)+(5*4)+(4*8)+(3*7)+(2*3)+(1*5)=145
145 % 10 = 5
So 1206487-35-5 is a valid CAS Registry Number.

1206487-35-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4,6-dibromopyridazin-3-amine

1.2 Other means of identification

Product number -
Other names 3-amino-4,6-dibromopyridazine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1206487-35-5 SDS

1206487-35-5Relevant articles and documents

PYRIDAZINE DERIVATIVES AS SMARCA2/4 DEGRADERS

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Page/Page column 56; 62, (2019/11/12)

The present invention provides pyridazine derivatives of formula (I), which are therapeutically useful as SMARCA2/4 degraders. These compounds are useful in the treatment and/or prevention of diseases or disorders dependent upon SMARCA2/4 in a mammal. The present invention also provides preparation of the compounds and pharmaceutical compositions comprising at least one of the pyridazine derivatives of formula (I) or a pharmaceutically acceptable salt, or a stereoisomer thereof.

COMBINATIONS FOR THE TREATMENT OF CANCER

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Page/Page column 136, (2014/02/16)

The present invention relates to combinations of at least two compounds A and B, compound A being an inhibitor of Mps-1 kinase, and compound B being an inhibitor of an anti-apoptotic protein of the Bcl-2 family. Another aspect of the present invention relates to the use of such combinations as described supra for the preparation of a medicament for the treatment or prophylaxis of a disease, particularly for the treatment of cancer. Another aspect of the present invention relates to the use of an anti- apoptotic protein from the Bcl-2 family as a sensitizer of cells to Mps-1 inhibitors. Another aspect of the present invention relates to the use of the ratio of pro-apoptotic and anti-apoptotic proteins from the Bcl-2 family in a biological sample as a biomarker for a Mps-1 kinase inhibitor treatment.

COMBINATION OF A IMIDAZOPYRIDAZINE DERIVATIVE AND A MITOTIC AGENT FOR THE TREATMENT OF CANCER

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Page/Page column 78; 79, (2015/01/09)

The present invention relates to a combination comprising an Mps-1 kinase inhibitor and a mitotic inhibitor. The present invention also relates to the use of said combination for the treatment of cancer, in particular of pancreatic cancer, glioblastoma, ovarian cancer, non-small cell lung carcinoma, breast cancer and/or gastric cancer.

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