88497-27-2 Usage
Description
6-BROMO-3-PYRIDAZINAMINE, also known as 6-bromopyridazin-3-amine, is a research chemical with a chemical formula of C5H4BrN4. It is a light brown to yellow solid and has a CAS number of 88497-27-2. 6-BROMO-3-PYRIDAZINAMINE is primarily used for research purposes in various scientific fields.
Uses
Used in Research Applications:
6-BROMO-3-PYRIDAZINAMINE is used as a research chemical for various scientific investigations. It is employed in the development and synthesis of new compounds, as well as in the study of chemical reactions and processes.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 6-BROMO-3-PYRIDAZINAMINE is used as an intermediate in the synthesis of various drugs and pharmaceutical compounds. Its unique chemical properties make it a valuable component in the development of new medications.
Used in Chemical Synthesis:
6-BROMO-3-PYRIDAZINAMINE is used as a starting material or building block in the synthesis of other organic compounds. Its reactivity and functional groups allow it to be easily incorporated into more complex molecules, making it a useful tool in organic chemistry.
Used in Material Science:
In the field of material science, 6-BROMO-3-PYRIDAZINAMINE may be used in the development of new materials with specific properties. Its unique structure and chemical characteristics can contribute to the creation of advanced materials with applications in various industries.
Used in Analytical Chemistry:
6-BROMO-3-PYRIDAZINAMINE can be employed as a reference compound or standard in analytical chemistry. It can be used to calibrate instruments, validate analytical methods, or as a control in experiments.
Overall, 6-BROMO-3-PYRIDAZINAMINE is a versatile research chemical with a wide range of applications across various scientific disciplines. Its unique properties and reactivity make it a valuable asset in the development of new compounds, materials, and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 88497-27-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,4,9 and 7 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 88497-27:
(7*8)+(6*8)+(5*4)+(4*9)+(3*7)+(2*2)+(1*7)=192
192 % 10 = 2
So 88497-27-2 is a valid CAS Registry Number.
InChI:InChI=1/C4H4BrN3/c5-3-1-2-4(6)8-7-3/h1-2H,(H2,6,8)
88497-27-2Relevant articles and documents
COMBINATIONS FOR THE TREATMENT OF CANCER
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Page/Page column 137, (2014/02/16)
The present invention relates to combinations of at least two compounds A and B, compound A being an inhibitor of Mps-1 kinase, and compound B being an inhibitor of an anti-apoptotic protein of the Bcl-2 family. Another aspect of the present invention relates to the use of such combinations as described supra for the preparation of a medicament for the treatment or prophylaxis of a disease, particularly for the treatment of cancer. Another aspect of the present invention relates to the use of an anti- apoptotic protein from the Bcl-2 family as a sensitizer of cells to Mps-1 inhibitors. Another aspect of the present invention relates to the use of the ratio of pro-apoptotic and anti-apoptotic proteins from the Bcl-2 family in a biological sample as a biomarker for a Mps-1 kinase inhibitor treatment.
COMBINATION OF A IMIDAZOPYRIDAZINE DERIVATIVE AND A MITOTIC AGENT FOR THE TREATMENT OF CANCER
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Page/Page column 79, (2015/01/09)
The present invention relates to a combination comprising an Mps-1 kinase inhibitor and a mitotic inhibitor. The present invention also relates to the use of said combination for the treatment of cancer, in particular of pancreatic cancer, glioblastoma, ovarian cancer, non-small cell lung carcinoma, breast cancer and/or gastric cancer.
