120711-54-8Relevant articles and documents
DENTRITIC POLYMERS, CROSSLINKED GELS, AND THEIR USES IN ORTHOPEDIC APPLICATIONS
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Page/Page column 271-272, (2010/10/20)
The present invention provides compositions, kits, and methods for repairing cartilaginous tissue. Certain methods of the invention utilize dendritic macromolecules formed by treating a dendritic compound with light or a linking compound. In certain instances, the dendritic compounds have a lysine, cysteine, isocysteine residue or other nucleophilic group attached to their peripheries. Addition of a compound containing two or more electrophilic groups, such as aldehydes, activated esters, or acrylates, to the lysine-capped, cysteine-capped, or isocysteine-capped dendrimers produces a polymeric compound that can repair a cartilage defect.
Dendritic macromers as in situ polymerizing biomaterials for securing cataract incisions
Wathier, Michel,Jung, Pil J.,Carnahan, Michael A.,Kim, Terry,Grinstaff, Mark W.
, p. 12744 - 12745 (2007/10/03)
Dendritic macromers are attractive macromolecules for hydrogel formation since high cross-linking densities at low polymer concentration can be obtained, varied physical properties can be observed based on the macromer structure, and low viscous aqueous s