1215-50-5

Basic information

• Product Name: 3-Anilino-1-phenyl-2-propen-1-one
• Synonyms: 3-Anilino-1-phenyl-2-propen-1-one
• CAS NO: 1215-50-5
• Molecular Formula: C₁₅H₁₃NO
• Molecular Weight: 223.26982
• Mol File: 1215-50-5.mol
• Article Data: 17

Chemical Properties

• Melting Point: 139-140 °C
• Boiling Point: 358.0±38.0 °C(Predicted)
• Appearance: /
• Density: 1.145±0.06 g/cm3(Predicted)
• PKA: 0.80±0.70(Predicted)
• CAS DataBase Reference: 3-Anilino-1-phenyl-2-propen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Anilino-1-phenyl-2-propen-1-one(1215-50-5)
• EPA Substance Registry System: 3-Anilino-1-phenyl-2-propen-1-one(1215-50-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 1215-50-5(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 3623-15-2 phenyl propargyl ketone 
• 3306-07-8 1-benzoyl-2-chloroethene 
• 1783-25-1 N₁,N₁-dimethyl-N₂-phenylformamidine 
• 98-86-2 acetophenone 
• 70769-76-5 3-ethylsulfanyl-1-phenyl-propenone 
• 72374-71-1 N-(2,2-dichloro-1-phenyl-1-propylidene)aniline 
• 142-04-1 aniline hydrochloride 
• 15397-33-8 3-Oxo-3-phenylpropanal 
• 67888-69-1 (E)-[1-phenylpropylidene]phenylamine 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 74896-59-6 β,β-diethylthioethyl phenyl ketone 
• 1201-93-0 1-phenyl-3-dimethylaminoprop-2-enone 
• 1131-80-2 (E)-3-(N,N-dimethylamino)-1-phenyl-2-propen-1-one 

Downstream Products

• 81404-72-0 1-phenyl-3-phenylimino-propane-1,2-dione-2-phenylhydrazone 
• 1006-67-3 5-phenylisoxazole 
• 1401856-17-4 (S)-5-benzoyl-1,4-diphenyl-3,4-dihydropyridin-2(1H)-one 
• 1401856-11-8 ((4S,6R)-6-hydroxy-4-(4-methoxyphenyl)-1-phenyl-1,4,5,6-tetrahydropyridin-3-yl)(phenyl)methanone 
• 1401856-10-7 ((4S,6R)-6-hydroxy-4-(2-methoxyphenyl)-1-phenyl-1,4,5,6-tetrahydropyridin-3-yl)(phenyl)methanone 
• 1373319-66-4 ethyl 1,3,5-triphenyl-1H-pyrrole-2-carboxylate 

Relevant articles and documents

An atom-economic green approach: Oxidative synthesis of functionalized 1,4-dihydropyridines from N,N-dimethylenaminones and amines

We report the first oxidative condensation between N,N-dimethylenaminones with amines to form 1,4-dihydropyridines in moderate to good yields, promoted by oxone and trifluoroacetic acid in PEG-400. This reaction features an unusual oxidation of in situ fo

Ambient aqueous-phase synthesis of covalent organic frameworks for degradation of organic pollutants

The development of a mild, low cost and green synthetic route for covalent organic frameworks (COFs) is highly desirable in order to open the door for practical uses of this new family of crystalline porous solids. Herein, we report a general and facile strategy to prepare a series of microporous or mesoporous COFs by a β-ketoenamine based Michael addition-elimination reaction in aqueous systems at ambient temperature and pressure. This synthesis method not only produces highly crystalline and porous COFs, but also can be carried out with a high reaction rate (only 30 min), high yields (as high as 93%) and large-scale preparation (up to 5.0 g). Furthermore, an Fe(ii)-doped COF shows impressive performance in the oxidative degradation of organic pollutants in aqueous medium. This research thus provides a promising pathway to large-scale green preparation of COFs and their potential application in environmental remediation.

Copper-catalyzed carbene insertion and ester migration for the synthesis of polysubstituted pyrroles

Copper-catalyzed carbene insertion/ester migration/cyclization of enaminones and α-diazo compounds occurred efficiently to afford 2-ester polysubstituted pyrroles under mild conditions in moderate-to-good yields. Substituent functionality was well tolerated and13C-labelled experiments demonstrated 1,2-ester migration during the reaction.

COMPOUNDS AND METHODS FOR HEMATOPOIETIC REGENERATION

The invention relates to compounds that promote hematopoietic regeneration. The invention further relates to methods of promoting hematopoietic regeneration using the novel compounds of the invention.