121734-80-3 Usage
Description
(R,R)-N-(1-Phenylethyl) Ibuprofen AMide, also known as the (R,R)-enantiomer of Ibuprofen (I140000) impurity, is a chiral compound derived from the well-known anti-inflammatory drug Ibuprofen. It exhibits a specific stereochemistry, with both the R-configuration at the chiral centers, which may result in different biological activities compared to other enantiomers. (R,R)-N-(1-Phenylethyl) Ibuprofen AMide has potential applications in the pharmaceutical and medical fields due to its anti-inflammatory properties.
Uses
Used in Pharmaceutical Industry:
(R,R)-N-(1-Phenylethyl) Ibuprofen AMide is used as an anti-inflammatory compound for its potential therapeutic effects in reducing inflammation and pain. Its specific stereochemistry may offer advantages in terms of efficacy and safety compared to other forms of Ibuprofen.
Used in Medical Research:
In the field of medical research, (R,R)-N-(1-Phenylethyl) Ibuprofen AMide can be utilized for studying the effects of stereochemistry on drug action, as well as for developing new drugs with improved pharmacological properties. Its anti-inflammatory activity makes it a valuable tool for investigating the underlying mechanisms of inflammation and pain relief.
Used in Drug Development:
(R,R)-N-(1-Phenylethyl) Ibuprofen AMide may also be employed in the development of new drugs with enhanced selectivity and reduced side effects. By understanding the specific interactions of this compound with biological targets, researchers can design more effective and safer medications for various inflammatory conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 121734-80-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,7,3 and 4 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 121734-80:
(8*1)+(7*2)+(6*1)+(5*7)+(4*3)+(3*4)+(2*8)+(1*0)=103
103 % 10 = 3
So 121734-80-3 is a valid CAS Registry Number.
121734-80-3Relevant articles and documents
BORONIC ACID CATALYSTS AND METHODS OF USE THEREOF FOR ACTIVATION AND TRANSFORMATION OF CARBOXYLIC ACIDS
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Page/Page column 61, (2012/09/10)
The present application provides methods and catalysts for activation of carboxylic acids for organic reactions. In particular, methods are disclosed for direct nucleophilic addition reactions, such as, amidation reactions with amines, cycloadditions, and conjugate additions, using boronic acid catalysts of formula I, II or III: Also included are novel boronic acid catalysts of formula IV, V and III:
N-Acyltrifluoromethanesulfonamides as new chemoselective acylating agents for aliphatic and aromatic amines
Guillard, Sophie,Aramini, Andrea,Cesta, Maria C.,Colagioia, Sandro,Coniglio, Silvia,Genovese, Filippo,Nano, Giuseppe,Nuzzo, Emanuela,Orlando, Valerie,Allegretti, Marcello
, p. 5608 - 5616 (2007/10/03)
This work describes advances in the study of the internal condensation of ammonium salts of N-acylsulfonamides. N-Acyltrifluoromethanesulfonamides show considerable advantages over the non fluorinated analogues by virtue of their higher reactivity and aci
