1217437-09-6

Basic information

• Product Name: α-(2-pyridyl-N-oxide)styrene
• Synonyms: α-(2-pyridyl-N-oxide)styrene
• CAS NO: 1217437-09-6
• Molecular Weight: 197.236
• Mol File: 1217437-09-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: α-(2-pyridyl-N-oxide)styrene(CAS DataBase Reference)
• NIST Chemistry Reference: α-(2-pyridyl-N-oxide)styrene(1217437-09-6)
• EPA Substance Registry System: α-(2-pyridyl-N-oxide)styrene(1217437-09-6)

Safety Data

• Hazardous Substances Data: 1217437-09-6(Hazardous Substances Data)

Upstream product

• 100-58-3 phenylmagnesium bromide 
• 1122-62-9 2-acetylpyridine 
• 19490-92-7 1-phenyl-1-(pyridin-2-yl)ethanol 
• 100393-43-9 α-phenyl-α-(2-pyridyl-N-oxide)ethanol 

Relevant articles and documents

Difunctionalization of Alkenylpyridine N-Oxides by the Tandem Addition/Boekelheide Rearrangement

A convenient and efficient approach for the difunctionalization of alkenylpyridine N-oxides through the tandem addition/Boekelheide rearrangement has been developed. The C-O and C-X (S, O, Cl) bonds are constructed simultaneously at the α- and β-positions under mild reaction conditions in 100% atom economy, which complements previously reported α- or β-functionalizations.

DiPAMP's big brother "i-Pr-SMS-Phos" exhibits exceptional features enhancing rhodium(I)-catalyzed hydrogenation of olefins

Switching Knowles DiPAMP's {DiPAMP = l,2-bis[(o-anisyl)(phenyl)phosphino] ethane} MeO groups with i-PrO ones led to the iPr-SMS-Phos {i-Pr-SMS-Phos = l,2-bis[(o-isopropoxyphenyl)(phenyl)phosphino]ethane} ligand which displayed a boosted catalyst activity coupled with an enhanced enantioselectivity in the rhodium(I)catalyzed hydrogenation of a wide-range of representative olefinic substrates (dehydro-a-amido acids, itaconates, acrylates, enamides, enol acetates, α,α-diarylethylenes, etc). The rhodium(I)-(i-PrSMS-Phos) catalytic profile was investigated revealing its structural attributes and robustness, and in contrast to the usual trend, 31P NMR analysis revealed that its methyl (Z)-α-acetamidocinnamate (MAC) adduct consisted of a reversed diastereomeric ratio of 1.4:1 in favour of the most reactive diastereomer.