1218948-44-7Relevant articles and documents
Diastereoselective synthesis of P-Stereogenic heterocycles via enyne ring-closing metathesis
Harvey, James Stephen,Giuffredi, Guy T.,Gouverneur, Veronique
, p. 1236 - 1239 (2010)
Chemical Equation Presented A range of P-containing ene-diynes suitable for desymmetrization was prepared via a two-step process starting from phosphorus oxychloride. In the presence of the Hoveyda-Grubbs II catalyst, these substrates underwent diastereoselective enyne ring-closing metathesis leading to various synthetically useful P-stereogenic heterocycles featuring an exocyclic alkynyl group. These products are amenable to further functional manipulation.