1220680-32-9

Basic information

• Product Name: 5-hydroxy-7-methoxy-6-(prop-2-enyl)flavanone
• Synonyms: 5-hydroxy-7-methoxy-6-(prop-2-enyl)flavanone
• CAS NO: 1220680-32-9
• Molecular Weight: 310.35
• Mol File: 1220680-32-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-hydroxy-7-methoxy-6-(prop-2-enyl)flavanone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-hydroxy-7-methoxy-6-(prop-2-enyl)flavanone(1220680-32-9)
• EPA Substance Registry System: 5-hydroxy-7-methoxy-6-(prop-2-enyl)flavanone(1220680-32-9)

Safety Data

• Hazardous Substances Data: 1220680-32-9(Hazardous Substances Data)

Upstream product

• 107-18-6 allyl alcohol 
• 75291-74-6 pinostrobin 
• 1220680-30-7 7-methoxy-5-(prop-2-enyloxy)flavanone 

Downstream Products

• 59718-54-6 5-hydroxy-7-methoxy-6-(3-methyl-but-2-enyl)flavanone 

Relevant articles and documents

Efficient microwave-assisted prenylation of pinostrobin and biological evaluation of its derivatives as antitumor agents

Pinostrobin (5-hydroxy-7-methoxyflavanone) obtained in relatively large amounts from fingerroot (Boesenbergia pandurata) was converted to its C-6 and C-8 prenylated derivatives. The Mitsunobu reaction, europium(III)-catalyzed Claisen-Cope rearrangement, and Claisen reaction coupled with cross-metathesis were used as the key steps. Using a sealed-vessel microwave reactor, the Mitsunobu and Claisen/Cope reactions occurred smoothly with short reaction times and in satisfactory yields. The target compounds and five new intermediary substances showed cytotoxic activity toward SK-BR-3, MCF-7, PC-3, and Colo-320DM human tumor cell lines, and all of them had significantly lower IC50 (μM) values than pinostrobin. Crown Copyright