122080-99-3

Basic information

• Product Name: 3-(4-Methylbenzenesulfonyl)-3- azabicyclo[3.2.0]heptan-6-one
• Synonyms: 3-(4-Methylbenzenesulfonyl)-3- azabicyclo[3.2.0]heptan-6-one;3-Tosyl-3-azabicyclo[3.2.0]heptan-6-one;3-(Toluene-4-sulfonyl)-3-aza-bicyclo[3.2.0]heptan-6-one;Cis-3-Tosyl-3-Azabicyclo[3.2.0]Heptan-6-One
• CAS NO: 122080-99-3
• Molecular Formula: C₁₃H₁₅NO₃S
• Molecular Weight: 265.3281
• Mol File: 122080-99-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 437.5±55.0 °C(Predicted)
• Appearance: /
• Density: 1.351±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• PKA: -5.91±0.20(Predicted)
• CAS DataBase Reference: 3-(4-Methylbenzenesulfonyl)-3- azabicyclo[3.2.0]heptan-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-Methylbenzenesulfonyl)-3- azabicyclo[3.2.0]heptan-6-one(122080-99-3)
• EPA Substance Registry System: 3-(4-Methylbenzenesulfonyl)-3- azabicyclo[3.2.0]heptan-6-one(122080-99-3)

Safety Data

• Hazardous Substances Data: 122080-99-3(Hazardous Substances Data)

Usage

General Description

3-(4-Methylbenzenesulfonyl)-3-azabicyclo[3.2.0]heptan-6-one is a chemical compound that belongs to the bicyclic lactam group. It has a molecular formula of C14H17NO3S and a molecular weight of 283.35 g/mol. 3-(4-Methylbenzenesulfonyl)-3- azabicyclo[3.2.0]heptan-6-one is commonly used as a building block in organic synthesis and pharmaceutical research due to its unique structure and reactivity. It has been studied for its potential pharmacological properties, including its potential as an enzyme inhibitor. The compound has also been investigated for its role in the development of novel drugs and therapeutic agents.

Upstream product

• 122080-91-5 3-{[(4-methylphenyl)sulfonyl]-N-(prop-2-en-1-yl)amino}-1-pyrrolidinylpropan-1-one 
• 42908-33-8 3-{[(4-methylphenyl)sulfonyl]amino}propanoic acid 
• 122081-15-6 3-{[(4-methylphenyl)sulfonyl]amino}-1-pyrrolidinylpropan-1-one 
• 98-59-9 p-toluenesulfonyl chloride 
• 61341-03-5 N-(toluene-4-sulfonyl)-β-alanyl chloride 

Downstream Products

• 663172-78-9 tert-butyl 6-hydroxy-3-azabicyclo[3.2.0]heptane-3-carboxylate 

Relevant articles and documents

TRICYCLIC GYRASE INHIBITORS

Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.