122091-57-0

Basic information

• Product Name: (-)-(R)-4-(p-tolyl)pentanal
• Synonyms: (-)-(R)-4-(p-tolyl)pentanal
• CAS NO: 122091-57-0
• Molecular Weight: 176.258
• Mol File: 122091-57-0.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: (-)-(R)-4-(p-tolyl)pentanal(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(R)-4-(p-tolyl)pentanal(122091-57-0)
• EPA Substance Registry System: (-)-(R)-4-(p-tolyl)pentanal(122091-57-0)

Safety Data

• Hazardous Substances Data: 122091-57-0(Hazardous Substances Data)

Upstream product

• 122091-56-9 (-)-(R)-4-(p-tolyl)pentan-1-ol 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 53448-06-9 pent-3-enal 
• 147030-70-4 3-(1,3-dioxolan-2-yl)-4'-methylpropiophenone 
• 159755-12-1 1-(1-bromoethyl)-4-methylbenzene 
• 536-50-5 CH₃C₆H₄CH(CH₃)OH 
• 122-00-9 para-methylacetophenone 
• 93922-51-1 (S)-2-(4-methylphenyl)-1-propanol 
• 196402-67-2 (R)-4-p-tolylpentanoic acid 
• 33596-66-6 2-(4-methylphenyl)propanal 
• 1374459-89-8 (R)-methyl 4-p-tolylpentanoate 
• 1086246-37-8 (E)-4-p-tolylpent-3-enoic acid 
• 1257661-37-2 (S)-1-methyl-4-(pent-4-en-2-yl)benzene 
• 503543-30-4 (R)-1-(1-bromopropan-2-yl)-4-methylbenzene 

Downstream Products

• 4176-17-4 (R)-(-)-α-curcumene 
• 1374307-58-0 (S,E)-6-p-tolylhept-2-en-1-ol 
• 1374307-57-9 (S,E)-ethyl 6-p-tolyhept-2-enoate 
• 196402-67-2 (R)-4-p-tolylpentanoic acid 
• 4179-25-3 (4S)-(4-methylphenyl)pentanoic acid 
• 78339-53-4 (S,Z)-2-methyl-6-(p-tolyl)hept-2-en-1-ol 
• 937207-96-0 1-(4-benzyl-2-thioxo-oxazolidin-3-yl)-3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-6-p-tolyl-heptan-1-one 
• 937207-97-1 toluene-4-sulfonic acid 3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-6-p-tolyl-heptyl ester 
• 937208-01-0 3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-6-p-tolyl-heptan-1-ol 
• 937207-98-2 3-methyl-2-(3-p-tolyl-butyl)-oxetane 
• 937207-95-9 1-(4-benzyl-2-thioxo-oxazolidin-3-yl)-3-hydroxy-2-methyl-6-p-tolyl-heptan-1-one 
• 25532-74-5 (+)-(S)-nuciferal 
• 807331-98-2 (S,E)-ethyl 2-methyl-6-p-tolylhept-2-enoate 
• 3649-81-8 (S)-curcumene 

Relevant articles and documents

Method for preparing chiral alkyl compound by catalyzing asymmetric hydrogenation reaction of olefin with iron complex catalyst

The invention discloses a method for preparing a chiral alkyl compound by catalyzing asymmetric hydrogenation reaction of olefin with an iron complex catalyst, which comprises the steps of by taking disubstituted olefin as shown in a formula I defined in

Method for preparing chiral alkyl compound through asymmetric catalytic hydrogenation of E/Z mixed or single-configuration trisubstituted olefin

The invention discloses a method for preparing a chiral alkyl compound through asymmetric catalytic hydrogenation of an E/Z mixed or single-configuration trisubstituted olefin. The method comprises following steps: taking a trisubstituted olefin represent

A asymmetric catalytic synthesis of (R)- 4, 7 - dimethyl - 1 - Tetralone method

The invention discloses a method for asymmetrically catalyzing and synthesizing (R)-4, 7-dimethyl-1-tetralone. According to the method, an asymmetrical Kumada cross coupling reaction is conducted on racemization 2-halogenated propionate ester catalyzed by bis oxazoline/ cobalt and a methyl phenyl grignard reagent, and (S)-P-toluene propionate ester 2 is firstly generated; then, (S)-P-toluene propionate ester 2 is reduced to (S)-P-toluene propyl alcohol 3 through diisobutylaluminium hydride (DIBAL-H), and then (R)-4-p-methylphenyl-1-amylene 5 is obtained through bromine generation and coupling with and vinyl grignard reagent; next, a hydroboration-oxidation reaction and a Dess-Martin oxidizing reaction are sequentially conducted, and (R)-4-p-methylphenyl valeraldehyde 6 is obtained; finally, oxidation is conducted through silver oxide, an intramolecular Fourier acyl reaction is conducted, and (R)-4,7-dimethyl-1-tetralone is obtained in a ring-closure synthesis mode. The synthesis route is simple and concise, 8 reactions are conducted in all, the total yield is 27%, and the optical purity of a product is 90%.