147030-70-4Relevant articles and documents
Dibromo-BODIPY as an Organic Photocatalyst for Radical-Ionic Sequences
Garciá-Santos, William H.,Ordó?ez-Hernández, Javier,Farfán-Paredes, Mónica,Castro-Cruz, Hiram M.,Maciás-Ruvalcaba, Norma A.,Farfán, Norberto,Cordero-Vargas, Alejandro
, p. 16315 - 16326 (2021/11/18)
A new dibrominated 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) is reported as a new metal-free photocatalyst. This BODIPY showed similar optoelectronic, electrochemical, and performance properties to those of Ru(bpy)3Cl2, one of the most common photocatalysts in a known radical-ionic transformation, such as the formation of 1,4-dicarbonyl compounds. Moreover, additional sequences in which the generated oxonium ion is trapped by an internal nucleophile were developed using this BODIPY photocatalyst. These new sequences allowed the straightforward preparation of ?3-alkoxylactones, monoprotected 1,4-ketoaldehydes, and dihydrofurans. This new catalyst, the methodology, and the forged functional groups could be important tools in organic synthesis.
Catalytic Asymmetric Synthesis of γ-Hydroxy Ketones and Aromatic Hydroxy Ketones by the Chemo- and Enantio-selective Alkylation of keto Aldehydes with Dialkylzincs
Watanabe, Masami,Soai, Kenso
, p. 3125 - 3128 (2007/10/02)
Optically active γ-hydroxy ketones and aromatic hydroxy ketones with high (up to 96percent) enantiomeric excesses have been synthesized by the chemo- and enantio-selective addition of dialkylzincs to γ-keto aldehydes and aromatic keto aldehydes, respectively, using N,N-dibutylnorephedrine (DBNE) 1 and (1-methylpyrrolidin-2-yl)diphenylmethanol (DPMPM) 5 as chiral catalysts.The method provides a non-homoaldol approach to optically active γ-hydroxy ketones.