1224103-58-5Relevant articles and documents
Design, synthesis and SAR of a novel series of heterocyclic phenylpropanoic acids as GPR120 agonists
Zhang, Xuqing,Cai, Chaozhong,Winters, Michael,Wells, Michele,Wall, Mark,Lanter, James,Sui, Zhihua,Ma, Jingyuan,Novack, Aaron,Nashashibi, Imad,Wang, Yuanping,Yan, Wen,Suckow, Arthur,Hua, Hong,Bell, Austin,Haug, Peter,Clapper, Wilma,Jenkinson, Celia,Gunnet, Joseph,Leonard, James,Murray, William V.
, p. 3272 - 3278 (2017/07/07)
A novel series of 5-membered heterocycle-containing phenylpropanoic acid derivatives was discovered as potent GPR120 agonists with low clearance, high oral bioavailability and in vivo antidiabetic activity in rodents.
