54840-34-5

Basic information

• Product Name: (4-ETHYL-PHENYL)-HYDRAZINE
• Synonyms: (4-ETHYL-PHENYL)-HYDRAZINE;AKOS BBS-00006810;1-(4-ETHYLPHENYL)HYDRAZINE
• CAS NO: 54840-34-5
• Molecular Formula: C₈H₁₂N₂
• Molecular Weight: 136.19
• Mol File: 54840-34-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 257.6 °C at 760 mmHg
• Flash Point: 126.2 °C
• Appearance: /
• Density: 1.056 g/cm³
• Vapor Pressure: 0.0144mmHg at 25°C
• Refractive Index: 1.603
• PKA: 5.42±0.20(Predicted)
• CAS DataBase Reference: (4-ETHYL-PHENYL)-HYDRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-ETHYL-PHENYL)-HYDRAZINE(54840-34-5)
• EPA Substance Registry System: (4-ETHYL-PHENYL)-HYDRAZINE(54840-34-5)

Safety Data

• Hazardous Substances Data: 54840-34-5(Hazardous Substances Data)

Usage

General Description

(4-Ethyl-phenyl)-hydrazine, also known as ethylbenzohydrazine, is a chemical compound with the formula C8H12N2. It is a hydrazine derivative, consisting of an ethyl group attached to a phenyl ring and a hydrazine functional group. (4-Ethyl-phenyl)-hydrazine is primarily used in organic chemistry as a building block for the synthesis of various pharmaceuticals and agrochemicals. It is also used as a reagent in the preparation of other organic compounds. Additionally, it has been studied for its potential as an anti-tumor agent, making it a compound of interest in the field of medicinal chemistry. However, it is important to handle (4-Ethyl-phenyl)-hydrazine with caution, as it is considered to be a hazardous material due to its toxic and carcinogenic properties.

InChI:InChI=1/C8H12N2/c1-2-7-3-5-8(10-9)6-4-7/h3-6,10H,2,9H2,1H3

Upstream product

• 589-16-2 4-aminoethylbenzene 

Downstream Products

• 1224103-58-5 3-(4-((1-(4-ethylphenyl)-1H-pyrazol-5-yl)methoxy)-2,3-dimethylphenyl)propanoic acid 
• 1586799-60-1 C₁₇H₁₆N₂ 
• 1586799-46-3 C₁₇H₁₈N₂ 
• 1415356-50-1 C₁₂H₁₀Cl₂N₂O 
• 1415356-12-5 C₁₉H₁₇ClN₂O₃ 
• 62500-88-3 2-(5-ethyl-1H-indol-3-yl)ethylamine 
• 1310575-22-4 6-ethyl-1-(2,3,4-trimethoxyphenyl)-2,3,4,9-tetrahydro-1H-β-carboline 
• 1310575-21-3 6-ethyl-1-(3,4-dimethoxyphenyl)-2,3,4,9-tetrahydro-1H-β-carboline 
• 1310575-20-2 6-ethyl-1-(4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-β-carboline 

Relevant articles and documents

Antioxydant activity of β-carboline derivatives in the LDL oxidation model

A series of β-carboline compounds were synthesized, starting from compound GWC22, their antioxidant activity was determined by inhibition of lipid peroxidation. The oxidation of LDL was induced in the presence of CuSO 4 or 2,2′-azobis(2-amidinopropane) dihydrochloride (AAPH). The protective actions of these compounds against the cytotoxicity were evaluated with lactate dehydrogenase (LDH) activity in bovine aortic endothelial cells (BAECs) and cellular vitality by measuring mitochondrial activity in the presence of MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide). Most of compounds showed an higher antioxidant activity than GWC22 derivative (R = 1.6 for 5 μM CuSO4). The best antioxidant activities are phenolic and benzyloxy derivatives with ratio R = 1.9 to 2.8 for 1 μM CuSO4. These substances have protective actions and increase significantly the cell viability.

Heterocyclic compounds

Optionally substituted 4-oxo-1,4-dihydrocinnolin-3-ylpropionic acid derivatives, processes for their preparation, pharmaceutical compositions containing them, and a method of treatment using them. A representative compound is ethyl 6-ethyl-1-methyl-4-oxo-