1225189-78-5Relevant articles and documents
Synthesis and evaluation of 5-substituted 9-hydroxypyrrolo[3,4-c]carbazole- 1,3(2H,6H)-diones as check point 1 kinase inhibitors
Sako, Yuki,Ichikawa, Satoshi,Osada, Akiko,Matsuda, Akira
experimental part, p. 7878 - 7889 (2011/02/23)
The structure-activity relationship (SAR) of 5-substituted pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione derivatives 5 was investigated for their potential as Chk1 inhibitors for possible chemo- and radio-potentiators in anticancer chemotherapies. In silico vi