122531-39-9

Basic information

• Product Name: 2-methyl-11-benzyl-2,3,4,5,6,11-hexahydro-1H-azocino<3,4-b>indol-1-one
• Synonyms: 2-methyl-11-benzyl-2,3,4,5,6,11-hexahydro-1H-azocino<3,4-b>indol-1-one
• CAS NO: 122531-39-9
• Molecular Weight: 318.418
• Mol File: 122531-39-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-methyl-11-benzyl-2,3,4,5,6,11-hexahydro-1H-azocino<3,4-b>indol-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-11-benzyl-2,3,4,5,6,11-hexahydro-1H-azocino<3,4-b>indol-1-one(122531-39-9)
• EPA Substance Registry System: 2-methyl-11-benzyl-2,3,4,5,6,11-hexahydro-1H-azocino<3,4-b>indol-1-one(122531-39-9)

Safety Data

• Hazardous Substances Data: 122531-39-9(Hazardous Substances Data)

Upstream product

• 2556-73-2 1-methyl-2-azepanone 
• 5705-15-7 N-benzyl-N-phenylhydrazine hydrochloride 
• 68-12-2 N,N-dimethyl-formamide 
• 72740-35-3 3-[1-Dimethylamino-meth-(Z)-ylidene]-1-methyl-azepan-2-one 

Relevant articles and documents

An improved synthesis of β-carboline and azepino-and azocino[3,4-b]indole derivatives from lactams

The Vilsmeier formylation of butyrolactam, N-methylbutyrolactam, N-methylvalerolactam, and N-methylcaprolactam followed by treatment with aryl hydrazines afforded the 2,3,4,9-tetrahydro-1H-β-carbolin-1-ones, 3,4,5,10-tetrahydroazepino[3,4-b]indol-1(2H)-ones, and 2,3,4,5,6,11-hexahydro- 1H-azocino[3,4-b]indol-1-ones. The synthesis was performed as a one-pot process without isolating the intermediate a-formyl lactams.

REACTIONS OF ARYLHYDRAZINES WITH α-FORMYL DERIVATIVES OF SIX- AND SEVEN-MEMBERED RING LACTAMS

Reactions of α-formyl derivatives of N-methyl-δ-valerolactam and N-methyl-ε-caprolactam with arylhydrazines lead to the formation of 3,4,5,10-tetrahydroazepinoindole-1(2H)-one and 2,3,4,5,6,11-hexahydro-1H-azocinoindol-1-one derivatives.As t