72740-35-3

Basic information

• Product Name: 3-[1-Dimethylamino-meth-(Z)-ylidene]-1-methyl-azepan-2-one
• CAS NO: 72740-35-3
• Molecular Weight: 182.266
• Mol File: 72740-35-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-[1-Dimethylamino-meth-(Z)-ylidene]-1-methyl-azepan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[1-Dimethylamino-meth-(Z)-ylidene]-1-methyl-azepan-2-one(72740-35-3)
• EPA Substance Registry System: 3-[1-Dimethylamino-meth-(Z)-ylidene]-1-methyl-azepan-2-one(72740-35-3)

Safety Data

• Hazardous Substances Data: 72740-35-3(Hazardous Substances Data)

Upstream product

• 2556-73-2 1-methyl-2-azepanone 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 122531-41-3 2-Methyl-11-phenyl-2,3,4,5,6,11-hexahydro-azocino[3,4-b]indol-1-one 
• 122510-77-4 4-(4-methylaminobutyl)-1-phenylpyrazol-5-one 
• 122531-38-8 2-methyl-2,3,4,5,6,11-hexahydro-1H-azocino<3,4-b>indol-1-one 
• 122531-39-9 2-methyl-11-benzyl-2,3,4,5,6,11-hexahydro-1H-azocino<3,4-b>indol-1-one 

Relevant articles and documents

An improved synthesis of β-carboline and azepino-and azocino[3,4-b]indole derivatives from lactams

The Vilsmeier formylation of butyrolactam, N-methylbutyrolactam, N-methylvalerolactam, and N-methylcaprolactam followed by treatment with aryl hydrazines afforded the 2,3,4,9-tetrahydro-1H-β-carbolin-1-ones, 3,4,5,10-tetrahydroazepino[3,4-b]indol-1(2H)-ones, and 2,3,4,5,6,11-hexahydro- 1H-azocino[3,4-b]indol-1-ones. The synthesis was performed as a one-pot process without isolating the intermediate a-formyl lactams.