1227210-33-4

Basic information

• Product Name: 5-Methyl-4,5,6,7-tetrahydro Pyrazolo[1,5-a]pyrazin-2-aMine
• Synonyms: 5-Methyl-4,5,6,7-tetrahydro Pyrazolo[1,5-a]pyrazin-2-aMine;4,5,6,7-tetrahydro-5-MethylPyrazolo[1,5-a]pyrazin-2-aMine
• CAS NO: 1227210-33-4
• Molecular Formula: C₇H₁₂N₄
• Molecular Weight: 152
• Mol File: 1227210-33-4.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 328.3±42.0 °C(Predicted)
• Appearance: /
• Density: 1.37±0.1 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 7.79±0.20(Predicted)
• CAS DataBase Reference: 5-Methyl-4,5,6,7-tetrahydro Pyrazolo[1,5-a]pyrazin-2-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methyl-4,5,6,7-tetrahydro Pyrazolo[1,5-a]pyrazin-2-aMine(1227210-33-4)
• EPA Substance Registry System: 5-Methyl-4,5,6,7-tetrahydro Pyrazolo[1,5-a]pyrazin-2-aMine(1227210-33-4)

Safety Data

• Hazardous Substances Data: 1227210-33-4(Hazardous Substances Data)

Usage

General Description

5-Methyl-4,5,6,7-Tetrahydro pyrazolo[1,5-a]pyrazin-2-amine is a chemical compound with a complex molecular structure. It belongs to the class of pyrazine derivatives and contains a tetrahydro pyrazolo core with a methyl group at the 5th position. 5-Methyl-4,5,6,7-Tetrahydro pyrazolo[1,5-a]pyrazin-2-amine has been studied for its potential pharmaceutical properties, including its role as a potential drug candidate for various medical conditions. Its chemical properties and structure make it a subject of interest in the field of medicinal chemistry and drug development. Further research and investigation are ongoing to explore its potential uses and applications in various domains such as pharmaceuticals, biotechnology, and chemical sciences.

Upstream product

• 1408327-48-9 5-methyl-2-nitro-6,7-dihydropyrazolo[1,5-a]pyrazine-4(5H)-one 
• 1360057-00-6 methyl 1-(2-bromoethyl)-3-nitro-1H-pyrazole-5-carboxylate 
• 1227210-31-2 1-(2-bromoethyl)-5-(bromomethyl)-3-nitro-1H-pyrazole 
• 1227210-30-1 (1-(2-bromoethyl)-3-nitro-1H-pyrazole-5-yl)methanol 
• 1227210-32-3 5-methyl-2-nitro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine 

Relevant articles and documents

Focal adhesion kinase inhibitor and use

The invention belongs to the field of medicines, relates to a focal adhesion kinase inhibitor and use, in particular relates to a novel focal adhesion kinase inhibitor compound, or stereoisomers, geometric isomers, tautomers, oxynitrides, hydrates, solvates, metabolites, pharmaceutically acceptable salts or prodrugs thereof, further relates to the use of the compound and pharmaceutical compositions as medicines, in particular the use of the compound and pharmaceutical compositions in manufacture of medicines for treatment or prevention of cancer, pulmonary hypertension, and pathological angiogenesis-related diseases.

SUBSTITUTED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF

The present disclosure relates to pyrimidine compounds of formula (I), their stereoisomers, tautomers, pharmaceutically acceptable salts, polymorphs, solvates, and hydrates thereof. The present disclosure also relates to process of preparation of these pyrimidine compounds, and to pharmaceutical compositions containing them. The compounds of the present disclosure are useful in the treatment, prevention or suppression of diseases and disorders mediated by epidermal growth factor receptor (EGFR) family kinases.

INHIBITORS OF BRUTON'S TYROSINE KINASE

This application discloses compounds according to generic Formula I: wherein the variables are defined as described herein, and which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with