123043-98-1Relevant articles and documents
Metalation of Biginelli compounds. A general unprecedented route to C-6 functionalized 4-aryl-3,4-dihydropyrimidinones
Singh, Kamaljit,Singh, Sukhdeep,Mahajan, Aman
, p. 6114 - 6117 (2005)
4-Aryl-6-methyl-3,4-dihydro-2(1H)-pyrimidinone esters (DHPMs) readily undergo metalation at the C-6 methyl (vinylogous ester) position on treatment with lithium diisopropylamide at -10 °C. The resulting anion intermediates can be treated with electrophili