1235514-53-0Relevant articles and documents
Interplay between the ribosomal tunnel, nascent chain, and macrolides influences drug inhibition
Starosta, Agata L.,Karpenko, Viktoriya V.,Shishkina, Anna V.,Mikolajka, Aleksandra,Sumbatyan, Natalia V.,Schluenzen, Frank,Korshunova, Galina A.,Bogdanov, Alexey A.,Wilson, Daniel N.
, p. 504 - 514 (2010)
Accumulating evidence suggests that, during translation, nascent chains can form specific interactions with ribosomal exit tunnel to regulate translation and promote initial folding events. The clinically important macrolide antibiotics bind within the ex
