1235528-02-5

Basic information

• Product Name: 3-(2-(1,4,5,6-tetrahydropyrimidinyl))benzonitrile
• Synonyms: 3-(2-(1,4,5,6-tetrahydropyrimidinyl))benzonitrile
• CAS NO: 1235528-02-5
• Molecular Weight: 185.228
• Mol File: 1235528-02-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-(2-(1,4,5,6-tetrahydropyrimidinyl))benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-(1,4,5,6-tetrahydropyrimidinyl))benzonitrile(1235528-02-5)
• EPA Substance Registry System: 3-(2-(1,4,5,6-tetrahydropyrimidinyl))benzonitrile(1235528-02-5)

Safety Data

• Hazardous Substances Data: 1235528-02-5(Hazardous Substances Data)

Upstream product

• 626-17-5 benzene-1,3-dicarbonitrile 
• 109-76-2 Trimethylenediamine 

Relevant articles and documents

1, 4, 5, 6-tetrahydro-pyrimidine derivative synthesis method

The invention discloses a novel method for synthesizing a 1,4,5,6-tetrahydropyrimidine derivative. The derivative is prepared through reaction between 2-aryl-substituted nitrile and 1,3-diaminopropane with copper cinnamate as a catalyst. The novel method has the advantages that the synthesis technology is simple and does not have strict requirements on reaction conditions, and the catalyst is cheap and can be reutilized, thereby facilitating actual production; the yield can reach 60%-90%.

A green and selective synthesis of 2-aryloxazines and 2- aryltetrahydropyrimidines

An efficient method for the selective synthesis of 2-substituted oxazines and tetrahydropyrimidines by the reaction of arylnitriles with 3-amino-1-propanol and 1,3-diaminopropane in the presence of montmorillonite K-10 and KSF as inexpensive, environmenta