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1235871-61-0

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1235871-61-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1235871-61-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,5,8,7 and 1 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1235871-61:
(9*1)+(8*2)+(7*3)+(6*5)+(5*8)+(4*7)+(3*1)+(2*6)+(1*1)=160
160 % 10 = 0
So 1235871-61-0 is a valid CAS Registry Number.

1235871-61-0Relevant articles and documents

Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives

Parhi, Ajit,Kelley, Cody,Kaul, Malvika,Pilch, Daniel S.,Lavoie, Edmond J.

, p. 7080 - 7083 (2013/01/15)

Antibiotic resistance has prompted efforts to discover antibiotics with novel mechanisms of action. FtsZ is an essential protein for bacterial cell division, and has been viewed as an attractive target for the development of new antibiotics. Sanguinarine is a benzophenanthridine alkaloid that prevents cytokinesis in bacteria by inhibiting FtsZ self-assembly. In this study, a series of 5-methylbenzo[c]phenanthridinium derivatives were synthesized and evaluated for antibacterial activity against Staphylococcus aureus and Enterococcus faecalis. The data indicate that the presence of a 1- or 12-phenyl substituent on 2,3,8,9-tetramethoxy-5-methylbenzo[c]phenanthridinium chloride significantly enhances antibacterial activity relative to the parent compound or sanguinarine.

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