1236-00-6 Usage
Description
19-Nortestosterone, 17-ethynyl-10-hydroxy-, also known as 10β-Hydroxynorethindrone, is a synthetic steroid hormone derived from the modification of the naturally occurring hormone, norethindrone. It is characterized by the presence of an ethynyl group at the 17th position and a hydroxyl group at the 10th position, which contribute to its unique chemical properties and biological activities.
Uses
Used in Pharmaceutical Industry:
19-Nortestosterone, 17-ethynyl-10-hydroxyis used as a progestin hormone for various contraceptive and hormonal applications. It is utilized in the development of combined oral contraceptives, where it works synergistically with estrogen to prevent ovulation, thicken cervical mucus, and alter the endometrial lining, thereby reducing the chances of pregnancy.
Additionally, 19-Nortestosterone, 17-ethynyl-10-hydroxyis used as a component in hormone replacement therapy (HRT) for women experiencing menopausal symptoms. It helps regulate hormonal imbalances and alleviate symptoms such as hot flashes, night sweats, and mood swings.
Furthermore, this synthetic steroid hormone is used in the treatment of certain gynecological conditions, such as endometriosis and heavy menstrual bleeding, due to its ability to regulate the menstrual cycle and reduce inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 1236-00-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,3 and 6 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1236-00:
(6*1)+(5*2)+(4*3)+(3*6)+(2*0)+(1*0)=46
46 % 10 = 6
So 1236-00-6 is a valid CAS Registry Number.
InChI:InChI=1/C20H26O3/c1-3-19(22)10-8-16-15-5-4-13-12-14(21)6-11-20(13,23)17(15)7-9-18(16,19)2/h1,12,15-17,22-23H,4-11H2,2H3/t15-,16-,17-,18-,19-,20+/m0/s1
1236-00-6Relevant articles and documents
Oxidation of lynestrenol by the fungus Cunninghamella elegans
Iqbal Choudhary,Atif
experimental part, p. 1 - 6 (2010/04/23)
Transformation of lynestrenol (19-nor-17α-pregn-4-en-20-yn-17β- ol) (1) was carried out by incubation with Cunninghamella elegans to obtain 19-nor-17α-pregn-4-en-20-yn-3-one-10β,17β-diol (2), 19-nor-17α-pregn-4-en-20-yn-3-one-6β,17β-diol (3), and 19-nor-17α-pregn-4-en-20-yn-3β,6β,17β-triol (4). Metabolite 4 was identified as a new compound. These metabolites were structurally characterised on the basis of spectroscopic techniques.