52-76-6 Usage
Chemical Properties
White or almost white, crystalline powder.
Uses
Different sources of media describe the Uses of 52-76-6 differently. You can refer to the following data:
1. Progestogen;Antioestrogen
2. Lynestrenol is an orally available progestogen hormone used in contraception to avoid hereditary angiodema as well as in treatment of ischemic stroke.
Brand name
Anacycline 101;Anacylin 101;Anacylin 28;Ancylin;Athilyn;Endometril;Exluton (a);Fysiognens;Fysionorm;Gestrol;Lindiol 2.5;Lyn_ratiopharm;Lyn_ratiophram_sequenz;Lyndeol;Lyndile tt;Lyndiol e.;Lyndiolett;Lynoenstrenol;Lyn-ratiopharm;Mini pregnon;Minifol;Minilyn;Neo lyndiol;Neo-lindiol;Neo-lynobol;Nonovulet;Noracyclin 22;Normophasic;Novostat;Org 485-50;Orgaluton;Orgametrol;Ovamezzo;Ovanone;Ovanon-e;Ovariostat;Ovoresta micro;Ovostat-28;Ovostat-micro;Phasicon;Physiostat;Physistat;Pregnon-28;Restovar.
World Health Organization (WHO)
Lynestrenol, a synthetic progestogen, was introduced in the early
1960s as a component in oral contraceptive preparations. In 1967, as a result of
new regulations required by the United States Food and Drug Administration,
lynestrenol was submitted to long-term toxicity studies and by the early 1970s it
was shown to be associated with an increased incidence of mammary tumours in
beagle bitches which led to its withdrawal by at least one regulatory authority.
Subsequently the validity of the beagle bitch model as a predictor of
carcinogenicity of steroid contraceptives has been contested by many national
regulatory authorities and lynestrenol remains available in some countries for
contraceptive and other purposes.
(Reference: (WHODI) WHO Drug Information, 1-3, 5-7, 1984)
Safety Profile
An experimental teratogen.Experimental reproductive effects. Human reproductiveeffects by ingestion and implant routes: menstrual cyclechanges or disorders, female fertility index, other fertilitychanges and effects on females. Questionable carcinoge
Check Digit Verification of cas no
The CAS Registry Mumber 52-76-6 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 5 and 2 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 52-76:
(4*5)+(3*2)+(2*7)+(1*6)=46
46 % 10 = 6
So 52-76-6 is a valid CAS Registry Number.
InChI:InChI=1/C20H28O/c1-3-20(21)13-11-18-17-9-8-14-6-4-5-7-15(14)16(17)10-12-19(18,20)2/h1,6,15-18,21H,4-5,7-13H2,2H3/t15-,16+,17+,18-,19-,20+/m0/s1
52-76-6Relevant articles and documents
Process for the production of 3-deoxy-4-ene steroids
-
, (2008/06/13)
A process for the production of 3-deoxy-4-ene steroids of the general formula I STR1 is described, in which R1, R2 and R3 mean a hydrogen atom or a methyl group, R4 represents a lower alkyl group, a phenyl group or a free, esterified or etherified hydroxy group, R5 symbolizes a hydrogen atom, a vinyl group or the grouping --C CR6 with R6 meaning a hydrogen atom, an alkyl group with a maximum of 4 carbon atoms or a halogen atom, X represents a methylene group, a fluoromethylene group, an ethylidene group or a vinylidene group, Y and U represent a methylene group or an ethylidene group and Z symbolizes a methylene group, an ethylidene group, a vinylidene group, a chloromethylene group or a hydroxymethylene group and in which the bonds represent three single bonds or one double bond and two single bonds or a conjugated double bond.