Basic Information | Post buying leads | Suppliers | Cas Database |
Name |
Lynestrenol |
EINECS | 200-151-4 |
CAS No. | 52-76-6 | Density | 1.08 g/cm3 |
PSA | 20.23000 | LogP | 4.31350 |
Solubility | N/A | Melting Point |
158 °C |
Formula | C20H28O | Boiling Point | 399.6 °C at 760 mmHg |
Molecular Weight | 284.442 | Flash Point | 176.9 °C |
Transport Information | N/A | Appearance | N/A |
Safety | Risk Codes | N/A | |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
19-Nor-17a-pregn-4-en-20-yn-17-ol(6CI,8CI);17a-Ethynyl-17b-hydroxyestr-4-ene;3-Desoxy-17a-ethinyl-19-nortestosterone;Exlutena;Exluton;Fysionorm;NSC 73879;Orgametrol;Physiostat;D4-17a-Ethinylestren-17b-ol; |
Article Data | 4 |
Conditions | Yield |
---|---|
With isopropyl alcohol |
Conditions | Yield |
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Multi-step reaction with 2 steps 1: acetone; CrO3; aqueous H2SO4 2: isopropyl alcohol View Scheme |
Conditions | Yield |
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In acetone |
Conditions | Yield |
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Stage #1: lynestrenol With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 1.5h; Inert atmosphere; Stage #2: allyl bromide In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 16h; Inert atmosphere; | 93% |
Conditions | Yield |
---|---|
Stage #1: lynestrenol With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 1.5h; Inert atmosphere; Stage #2: bromopentene In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 16h; Inert atmosphere; | 49% |
lynestrenol
Conditions | Yield |
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With lithium aluminium tetrahydride; aluminium trichloride In tetrahydrofuran |
lynestrenol
Conditions | Yield |
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With hematoporphyrin In methanol at 15℃; Rate constant; Irradiation; pH 7.7; |
lynestrenol
1-((8R,9S,10R,13S,14S,17S)-17-Hydroxy-13-methyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-ethanone
Conditions | Yield |
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With sulfuric acid; mercury(II) oxide |
lynestrenol
Conditions | Yield |
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With deuterium; palladium on activated charcoal In ethanol |
lynestrenol
Conditions | Yield |
---|---|
With sulfuric acid; mercury(II) oxide |
Chemical Name: Lynestrenol
IUPAC NAME: (8R,9S,10R,13S,14S,17R)-17-Ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol
CAS No.: 52-76-6
Molecular Formula: C20H28O
Molecular Weight: 284.44 g/mol
Melting Point: 158°C
Density: 1.08 g/cm3
Flash Point: 176.9 °C
Boiling Point: 399.6 °C at 760 mmHg
Following is the structure of 19-Nor-17-α-pregn-4-en-20-yn-17-ol (52-76-6):
Product Categories about 19-Nor-17-α-pregn-4-en-20-yn-17-ol (52-76-6) are Steroids ; Hormone ; Intracellular receptor
The chemical synonymous of 19-Nor-17-α-pregn-4-en-20-yn-17-ol (52-76-6) are 4-Estren-17-alpha-ethynyl-17-beta-ol ; 4-Estren-17a-ethinyl-17beta-ol ; 19-Nor-17-alpha-pregn-4-en-20-yn-17-l ; Ethinylestrenol ; Lynoestrenol ; Lynestrenol ; (17-Alpha)-19-norpregn-4-en-20-yn-17-ol ; 17-Alpha-ethinyl-17-beta-hydroxyestr-4-ene
IARC Cancer Review: Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 21 ,1979,p. 407.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .
An experimental teratogen. Experimental reproductive effects. Human reproductive effects by ingestion and implant routes: menstrual cycle changes or disorders, female fertility index, other fertility changes and effects on females. Questionable carcinogen. Used in oral contraceptives and in the treatment of dysfunctional uterine bleeding. When heated to decomposition it emits acrid smoke and irritating fumes.