124-28-7 Usage
Description
N,N-Dimethyloctadecylamine, also known as N,N-Dimethyloctadecan-1-amine, is a clear yellow liquid with a fish-like odor. It is insoluble in water and less dense than water, causing it to float on water's surface. This chemical may irritate skin, eyes, and mucous membranes, and it has the potential to be toxic through ingestion, inhalation, or skin absorption. Primarily used as a chemical intermediate, N,N-Dimethyloctadecylamine is instrumental in the production of various compounds and surfactants.
Uses
Used in Chemical Synthesis:
N,N-Dimethyloctadecylamine is used as a chemical intermediate for the manufacture of quaternary ammonium compounds, amine oxide, and betaine surfactants. These compounds are essential in various industries, including pharmaceuticals, cosmetics, and cleaning products, due to their antimicrobial, emulsifying, and foaming properties.
Used in Tannic Acid Cross-Linking:
N,N-Dimethyloctadecylamine serves as a useful reagent for the preparation of cationic gelatin cross-linked with Tannic Acid (T006560(P)). This cross-linking process enhances the properties of gelatin, making it suitable for applications in the biomedical and materials science fields, such as tissue engineering and drug delivery systems.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
N,N-Dimethyloctadecylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Health Hazard
TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire Hazard
Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
Check Digit Verification of cas no
The CAS Registry Mumber 124-28-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,2 and 4 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 124-28:
(5*1)+(4*2)+(3*4)+(2*2)+(1*8)=37
37 % 10 = 7
So 124-28-7 is a valid CAS Registry Number.
InChI:InChI=1/C20H43N/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21(2)3/h4-20H2,1-3H3
124-28-7Relevant articles and documents
DNA STRONGLY BINDS TO MICELLES AND VESICLES CONTAINING LIPOPOLYAMINES OR LIPOINTERCALANTS.
Behr, Jean-Paul
, p. 5861 - 5864 (1986)
Gel electrophoresis and U.V. spectroscopy show that DNA binds to the surfaces of both small unilamellar vesicles and micelles coated with trisammonium or acridinyl-trisammonium head groups.
Photochemical Cleavage of Benzylic C-N Bond to Release Amines
Wang, Pengfei,Devalankar, Dattatray A.,Lu, Wenya
, p. 6195 - 6200 (2016/08/16)
The 3-(diethylamino)benzyl (DEABn) group has been studied for releasing primary, secondary, and tertiary amines by direct photochemical breaking of the benzylic C-N bond. While photochemical release of primary and secondary amines provides high yields in
Vernonia oil: Conversion to a mixture of tertiary amines including N,N-Dimethyl-(12S,13R)-Epoxy-cis-9-Octadecenyl amine
Johnson, Nikki S.,Ayorinde, Folahan O.
experimental part, p. 1425 - 1430 (2011/11/11)
Vernonia galamensis is a new potential industrial oilseed crop found in tropical Africa. It is the source of a naturally epoxidized oil called vernonia oil (VO) which is extracted from the seed of the plant. In this study VO was used as the starting material for the synthesis of a mixture of amines, with the major product amine being N,N-dimethyl-(12S,13R)-epoxy-cis-9-octadecenyl amine. VO was transesterified via a base catalyzed methanolysis using sodium methoxide to yield VO methyl esters (VOME). Aminolysis of the VOME with dimethylamine as reagent and solvent under reflux conditions afforded the tertiary amides, with N,N- dimethyl-(12S,13R)-epoxy-cis-9-octadecenyl amide as the major product. The mixture was then subjected to metal hydride reduction with lithium aluminum hydride in diethylether under reflux conditions to obtain the desired amine mixture including N,N-dimethyl-(12S,13R)-epoxy-cis-9-octadecenyl amine. Electron impact mass spectrometry was used to characterize the mixture of amines. Additionally, proton NMR, 13C NMR, and FTIR were used for characterization of N,N-dimethyl-(12S,13R)-epoxy-cis-9-octadecenyl amine. To further confirm the conversion of VO to the amines, the quaternary ammonium salts were synthesized and characterized by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.
METHOD OF PRODUCING NITROGEN-CONTAINING COMPOUND
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Page/Page column 10, (2009/10/01)
The present invention provides a process for producing high-purity aliphatic tertiary amines containing a less amount of by-products by using a chromium-free catalyst with a good productivity in an economically advantageous manner. The present invention relates to a process for producing a tertiary amine by reducing an amide compound in the presence of a catalyst containing copper and magnesium at a molar ratio of magnesium to copper (magnesium/copper) of from 0.01 to 20.