1240693-60-0

Basic information

• Product Name: C₁₇H₁₀ClF₂N₃
• CAS NO: 1240693-60-0
• Molecular Weight: 329.736
• Mol File: 1240693-60-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₀ClF₂N₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₀ClF₂N₃(1240693-60-0)
• EPA Substance Registry System: C₁₇H₁₀ClF₂N₃(1240693-60-0)

Safety Data

• Hazardous Substances Data: 1240693-60-0(Hazardous Substances Data)

Upstream product

• 367-21-5 3-chloro-4-fluorophenylamine 
• 61338-20-3 C₁₀H₅FN₂O 
• 326915-70-2 C₁₂H₁₁FN₂O₂ 
• 77898-24-9 3-chloro-4-fluoro-N-methylaniline 
• 886362-73-8 4-chloro-6-fluoroquinoline-3-carbonitrile 
• 297150-27-7 C₁₃H₁₀ClFN₄ 

Relevant articles and documents

Synthesis and cytotoxicity studies of quinoline-3-carbonitrile derivatives

A series of quinoline-3-carbonitrile derivatives were designed and synthesized. Their cytotoxicity in vitro against four cancer cell lines (A549, HT-29, MDA-MB-231 and SMMC-7721) were evaluated by standard MTT assay. The pharmacological results showed that most of the prepared compounds displayed excellent selective cytotoxicity toward SMMC-7721 cell line. Among them, compounds 7c, 7e, 11b, 11f and 11g were more active than Gefitinb against SMMC-7721 cell line.