1241901-39-2Relevant articles and documents
Spiroheterocycles via regioselective cycloaddition reactions of nitrile oxides with 5-methylene-1H-pyrrol-2(5H)-ones
Beattie, Nicola J.,Francis, Craig L.,Liepa, Andris J.,Savage, G. Paul
experimental part, p. 445 - 451 (2010/08/06)
Substituted 5-methylene-1H-pyrrol-2(5H)-ones underwent a 1,3-dipolar cycloaddition reaction with nitrile oxides to give the corresponding spiro heterocycles. Critical to this reaction was the development of a biphasic system for base-induced dehydrohaloge