1246175-29-0Relevant articles and documents
Simple assembly of polysubstituted pyrazoles and isoxazoles via ring closure-ring opening domino reaction of 3-acyl-4,5-dihydrofurans with hydrazines and hydroxylamine
Chagarovskiy, Alexey O.,Budynina, Ekaterina M.,Ivanova, Olga A.,Rybakov, Victor B.,Trushkov, Igor V.,Melnikov, Mikhail Ya.
, p. 2905 - 2915 (2016/03/12)
A convenient general approach to 2-(pyrazol-4-yl)- and 2-(isoxazol-4-yl)ethanols based on the Br?nsted acid-initiated reaction of 3-acyl-4,5-dihydrofurans with hydrazines or hydroxylamine was developed. Further transformation of the alcohol moiety in 2-(pyrazolyl)ethanols affording 2-(pyrazolyl)ethylamine as potent bioactive compounds as well as pyrazole-substituted derivatives of antitumor alkaloid crispine A was elaborated.
An efficient, transition-metal-free process for the synthesis of substituted dihydrofurans via a Michael/cyclization tandem reaction
Wu, Ming-Yu,Wang, Ming-Qi,Li, Kun,Feng, Xing-Wen,He, Ting,Wang, Na,Yu, Xiao-Qi
, p. 679 - 683 (2011/03/21)
An efficient green route for the synthesis of substituted dihydrofurans was developed through a simple base-catalyzed, tandem reaction of nitrostyrene with 1,3-dicarbonyl compounds. The desired products were prepared with a large substrate scope and in excellent yields (up to 95%).
