15725-17-4

Basic information

• Product Name: 3-(4-Methoxybenzylidene)pentane-2,4-dione
• Synonyms: 2-Acetyl-1-(4-methoxyphenyl)-1-buten-3-one;3-(4-Methoxybenzylidene)-2,4-pentanedione;3-(4-Methoxybenzylidene)pentane-2,4-dione
• CAS NO: 15725-17-4
• Molecular Formula: C₁₃H₁₄O₃
• Molecular Weight: 218.2485
• Mol File: 15725-17-4.mol
• Article Data: 24

Chemical Properties

• Melting Point: 208 °C
• Boiling Point: 417.1°Cat760mmHg
• Flash Point: 187.9°C
• Appearance: /
• Density: 1.102g/cm³
• Vapor Pressure: 3.63E-07mmHg at 25°C
• Refractive Index: 1.545
• CAS DataBase Reference: 3-(4-Methoxybenzylidene)pentane-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-Methoxybenzylidene)pentane-2,4-dione(15725-17-4)
• EPA Substance Registry System: 3-(4-Methoxybenzylidene)pentane-2,4-dione(15725-17-4)

Safety Data

• Hazardous Substances Data: 15725-17-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H14O3/c1-9(14)13(10(2)15)8-11-4-6-12(16-3)7-5-11/h4-8H,1-3H3

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 123-54-6 acetylacetone 
• 41002-50-0 4-acetoxy-3-penten-2-one 
• 19350-72-2 N'-(4-methoxybenzylidene)-4-methylbenzenesulfonohydrazide 
• 15435-71-9 sodium acetylacetonate 

Downstream Products

• 1246175-29-0 1-(4-(4-methoxyphenyl)-2-methyl-4,5-dihydrofuran-3-yl)ethanone 
• 87388-56-5 C₁₃H₁₃NO₂ 
• 1399383-19-7 dimethyl 4-acetyl-8-methoxy-3-methyl-2-benzoxepine-1,1(3H)-dicarboxylate 
• 1399383-06-2 dimethyl 4-acetyl-3-(4-methoxyphenyl)-5-methylfuran-2,2(3H)-dicarboxylate 
• 1399383-40-4 ethyl 4-acetyl-1,3-dihydro-8-methoxy-3-methyl-2-benzoxepine-1-carboxylate 
• 1399383-29-9 ethyl 4-acetyl-2,3-dihydro-3-(4-methoxyphenyl)-5-methylfuran-2-carboxylate 
• 1240983-15-6 ethyl 3-acetyl-4-hydroxy-2-(4-methoxyphenyl)-4-methyl-6-oxocyclohexanecarboxylate 

Relevant articles and documents

Antimicrobial, antioxidant and SOD activities of copper(II) complexes derived from 2-aminobenzothiazole derivatives

A series of Cu(II) complexes have been synthesized from bidentate Schiff base ligands (by condensation of Knoevenagel condensate of acetoacetanilide (obtained from substituted benzaldehydes and acetoacetanilide) and 2-aminobenzothiazole). They were charac

Corrigendum to: Enzyme Promiscuity as a Remedy for the Common Problems with Knoevenagel Condensation (Chemistry – A European Journal, (2019), 25, 43, (10156-10164), 10.1002/chem.201901491)

In the published paper, there is a mistake in the labelling of compounds in Figure. A corrected version of that Figure appears below. The authors apologise for the mistake. Figure (Figure presented.) Unsaturated 2,4-pentanediones obtained by enzyme-catalyzed tandem Knoevenagel reaction. Reaction conditions: aldehyde (1 mmol), 4-acetoxy-3-penten-2-one (5 a, R1=R2=R3=Me) (3 mmol), and PPL (100 mg) in tert-butyl alcohol/ 5 % H2O v/v (2 mL) for 72 h at 20 °C, 200 rpm. [a] With vinyl acetate. [b] With ethyl β-styrylcarbonate. [c] With styryl acetate.

Base-Promoted Tandem Cyclization for the Synthesis of Benzonitriles by C?C Bond Construction

A facile synthesis of benzonitriles via a base-promoted tandem cyclization reaction of α,β-unsaturated enones having electron-withdrawing group (EWG) and 2-acyl-acrylonitriles was developed. This new synthetic method to access benzonitriles is suitable for a wide range of substrates. A plausible reaction mechanism is proposed on the basis of previous literature and our own investigations. (Figure presented.).