1246523-57-8

Basic information

• Product Name: methyl 2-(7-hydroxy-5-methoxy-3-(4-methoxyphenethyl)-1,4-bis(4-methoxyphenyl)-3,6-dihydropyrrolo[2,3-c]carbazol-2-yl)-2-(4-methoxyphenyl)acetate
• Synonyms: methyl 2-(7-hydroxy-5-methoxy-3-(4-methoxyphenethyl)-1,4-bis(4-methoxyphenyl)-3,6-dihydropyrrolo[2,3-c]carbazol-2-yl)-2-(4-methoxyphenyl)acetate
• CAS NO: 1246523-57-8
• Molecular Weight: 776.886
• Mol File: 1246523-57-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl 2-(7-hydroxy-5-methoxy-3-(4-methoxyphenethyl)-1,4-bis(4-methoxyphenyl)-3,6-dihydropyrrolo[2,3-c]carbazol-2-yl)-2-(4-methoxyphenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(7-hydroxy-5-methoxy-3-(4-methoxyphenethyl)-1,4-bis(4-methoxyphenyl)-3,6-dihydropyrrolo[2,3-c]carbazol-2-yl)-2-(4-methoxyphenyl)acetate(1246523-57-8)
• EPA Substance Registry System: methyl 2-(7-hydroxy-5-methoxy-3-(4-methoxyphenethyl)-1,4-bis(4-methoxyphenyl)-3,6-dihydropyrrolo[2,3-c]carbazol-2-yl)-2-(4-methoxyphenyl)acetate(1246523-57-8)

Safety Data

• Hazardous Substances Data: 1246523-57-8(Hazardous Substances Data)

Upstream product

• 20289-27-4 7-benzyloxyindole 
• 1493-27-2 ortho-nitrofluorobenzene 
• 50612-99-2 methyl 2-bromo-2-(4-methoxyphenyl)acetate 
• 123-11-5 4-methoxy-benzaldehyde 
• 127517-27-5 2-(tert-butoxy)aniline 
• 83747-12-0 2-(tert-butoxy)-1-nitrobenzene 
• 23786-14-3 4-methoxy-phenyl acetic acid methyl ester 
• 3179-10-0 (E)-1-methoxy-4-(2-nitrovinyl)benzene 
• 702-23-8 2-(4-Methoxyphenyl)ethanol 
• 14425-64-0 4-methoxyphenethyl bromide 
• 1246523-41-0 4-bromo-6-methoxy-3,7-bis-(4-methoxy-phenyl)-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester 
• 1246523-40-9 1-(1-(2,6-dibromo-4-methoxyphenyl)-2-nitroethyl)-4-methoxybenzene 
• 1246523-39-6 tert-butyl 2-(2,6-dibromo-4-methoxyphenyl)-2-(4-methoxyphenyl)ethylcarbamate 
• 1246523-38-5 4-bromo-6-methoxy-1-(4-methoxyphenethyl)-3,7-bis(4-methoxyphenyl)-1H-indole 

Downstream Products

• 1246523-47-6 methyl 2-(5-methoxy-3-(4-methoxyphenethyl)-1,4-bis(4-methoxyphenyl)-7-(2,2,2-trichloroethoxysulfonyloxy)-3,6-dihydropyrrolo[2,3-c]carbazol-2-yl)-2-(4-methoxyphenyl)acetate 
• 1246523-58-9 methyl 2-(5-hydroxy-3-(4-hydroxyphenethyl)-1,4-bis(4-hydroxyphenyl)-7-(2,2,2-trichloroethoxysulfonyloxy)-3,6-dihydropyrrolo[2,3-c]carbazol-2-yl)-2-(4-methoxyphenyl)acetate 
• 1246657-85-1 dictyodendrin A 

Relevant articles and documents

Concise syntheses of dictyodendrins A and F by a sequential C-H functionalization strategy

Syntheses of dictyodendrins A and F have been achieved using a sequential C-H functionalization strategy. The N-alkylpyrrole core is fully functionalized by means of a rhodium(I)-catalyzed C-H arylation at the C3-position, a rhodium(II)-catalyzed double C-H insertion at the C2- and C5-positions, and a Suzuki-Miyaura cross-coupling reaction at the C4-position. The syntheses of dictyodendrins A and F were completed by formal 6π-electrocyclization to generate the pyrrolo[2,3-c]carbazole core of the natural products.

Total synthesis of dictyodendrin A and B

(Figure Presented) In-do-line of fire: A highly efficient total synthesis of the title compounds features a novel benzyne-mediated one-pot indoline formation/cross-coupling sequence for the construction of a highly substituted key indoline intermediate. The peripheral substituents were then introduced onto the intermediate in a modular fashion to complete the total syntheses of dictyodendrin A and B.